inflammatory response Flashcards
1
Q
purpose of inflammatory response
A
-defend against potential pathogens
-eliminate effects of an injury
-clear out damaged/destroyed cells
-initiate repair
2
Q
three main stages of inflammatory response
A
- initiation
- vasodilation
- migration
3
Q
initiation
A
-pathogens are introduced in the body during injury
-immune cells in nearby tissues release cytokines
-mast cells degranulate, releasing histamine
4
Q
vasodilation
A
histamine released binds to receptors on nearby blood vessels, causing :
-vasodilation
-increased permeability of blood vessels
-attraction of phagocytes
5
Q
migration
A
many components of the innate immune system can now enter the site of injury as a result of widening of blood vessels, and increased permeability, including :
-phagocytes that have been attracted by cytokines
-complement proteins
