Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Phys Agents > Inflammation and Healing Process > Flashcards

Inflammation and Healing Process Flashcards

1
Q

What are the 4 phases of injury and repair

A
  1. Hemostasis
  2. Inflammatory phase
  3. Proliferation phase
  4. Maturation phase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When does hemostasis occur

A

Immediately after injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How long does the inflammatory phase last

A

1-6 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How long does the proliferation phase last

A

3-20 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How long does the maturation phase last

A

Day 9 and on

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is diapedesis

A

Squeezing through vessel walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is blood accumulated in tissue

A

Hematoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is blood accumulated in a joint

A

Hemarthrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the equation for capillary filtration pressure (CFP)

A

CFP=(CHP+TOP)-(THP+COP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is CHP

A

Capillary hydrostatic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is COP

A

Capillary osmotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is hydrostatic pressure

A

Pressure exerted by a column of water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is osmotic pressure

A

Pressure resulting from attraction f fluid by free proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Does hydrostatic pressure pull or push water

A

Pushes water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Does osmotic pressure pull or push water

A

Pulls water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the 3 polymorphonuclear leukocytes

A
  1. Neutrophils
  2. Basophils
  3. Eosinophils
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

When are polymorphonuclear leukocytes released

A

The first 24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What do neutrophils do

A

Phagocytosis and release protease and collagenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What do basophils do

A

Release histamine and increase vascular permeability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What do eosinophils do

A

Phagocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the 2 mononuclear leukocytes

A
  1. Monocytes

2. Lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

When are the mononuclear leukocytes released

A

Hours 24-48

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are monocytes converted to

A

Converted to macrophages, collagenase, fribronectin, hydrogenperoxide, ascorbic acid, and lactic acid

24
Q

When are monocytes most effective

A

In O2 rich environment

25
Q

What do lymphocytes do

A

Supply antibodies

26
Q

What do B lymphocytes do

A

Release antibodies into the bloodstream

27
Q

What do T lymphocytes do

A

Assist B cells in regulation of cloning

28
Q

What does hypoxia do (4)

A
  1. Switch from aerobic to anaerobic metabolism
  2. Decreases ATP production
  3. Decreases cell membrane function
  4. Increase cellular acidosis
29
Q

How does hypoxia affect cell membrane function (3)

A
  1. Na pump slows or stops
  2. [Na] in cell increases
  3. [H2O] increases, cell swells, bursts
30
Q

What is the process of making collagen from fibroblasts (6)

A
  1. Fibroblasts
  2. Procollagen
  3. Tropocollagen
  4. Collagen fibrils
  5. Collagen filaments
  6. Collagen fibers
31
Q

What is granulation tissue

A

Tissue composed of capillaries, fibroblasts, and myofibroblasts

32
Q

What type of collagen is initially formed

A

Type III

33
Q

When does type III collagen begin to be replaced by type I collagen

A

By day 12

34
Q

When do the edges of the wound start to pull together

A

5 days after injury

35
Q

How long does it take the wound to close in muscle or skin

A

5-8 days

36
Q

How long does it take the wound to close in ligament or tendon

A

3-6 weeks

37
Q

What is angiogenesis

A

Growth of new blood vessels

38
Q

What does the scar tissue remaining redder than the surrounding tissue mean

A

The scar tissue is still remodeling

39
Q

What is the induction theory of collagen fiber orientation

A

Scars attempt to mimic characteristics of injured tissue

40
Q

What is the tension theory of collagen fiber orientation

A

Internal and external stresses applied during the maturation phase determine the final tissue structure

41
Q

What is regeneration

A

Restoration of the tissue that is identical to the injured tissue

42
Q

What is repair

A

Fibrous scar formation and structural and functional properties of injured tissue altered

43
Q

What is ideal healing

A

Normal structure, function, and appearance

44
Q

What is acceptable healing

A

Almost normal structure and appearance but less than optimal function

45
Q

What is minimal healing

A

Some normal structure, function, appearance

46
Q

What is failed healing

A

Abnormal structure, function, and appearance

47
Q

Where does a grade I and II articular cartilage tear occur

A

Superficial layers of cartilage

48
Q

Where does a grade III articular cartilage tear occur

A

Near the subchondral bone

49
Q

What does ice do

A

Limits secondary injury

50
Q

How does ice limit secondary injury (2)

A

Metabolically or chemically

51
Q

How does ice prevent secondary injury chemically

A

Limits permeability thus leakage of protein rich fluid into the tissue decreases

52
Q

How does ice prevent secondary injury metabolically

A

Causes O2 debt leads to anaerobic metabolism, which is slower than aerobic metabolism

53
Q

What does compression do (3)

A
  1. Increase external capillary pressure
  2. Decrease CFP
  3. Decreases edema formation
54
Q

What does elevation do

A

Decreases capillary hydrostatic pressure

55
Q

What does protection/stabilization do (2)

A
  1. Allows muscle to relax

2. Reduces pain and neural inhibition

Phys Agents (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions