Inflammation Flashcards

1
Q

2 negative acute phase reactants to inflammation?

A

haemoglobin

albumin

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2
Q

T1DM Target tissue and antigen?

A

B-islet Cells

surface Antigen of islet cells

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3
Q

RA target tissue and antigen?

A

synovial membrane

IgM (Fc)

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4
Q

goodpasture’s target tissue and antigen?

A

kidneys, lungs,

Type 4 collagen (basement membrane)

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5
Q

ANCA target tissue and antigen?

A

kidneys, lungs, sinuses

cytoplasmic components of neutrophils

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6
Q

grave’s disease target tissue and antigen?

A

thyroid

TSH receptor, TPO, thyroglobulin

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7
Q

rash from coeliac called?

A

dermatitis herpetiformis

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8
Q

most common vasculitis?

A

giant cell arteritis

no known trigger

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9
Q

how does stenosis differ in giant cell vs. atherosclerosis?

A

giant cell: tapering stenosis

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10
Q

how do you get antinuclear antibodies in Lupus?

A

cellular debris from apoptosis become DAMPS/PAMPS

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11
Q

malar rash from SLE different how?

A

sparing of nasal labial fold

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12
Q

biological copper carrier called?

A

caeruloplasmin

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