Dermatology II Flashcards

1
Q

where does atopic eczema usually occur? look like?

A

ill defined
scaly
patches
in flexures

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2
Q

what is filaggrin mutation?

A

genetic reduced skin barrier function, more likely atopic eczema

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3
Q

atopic eczema happens where on infant more likely?

A

face

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4
Q

what is lichenification?

A

chronic rubbing/scratching of atopic eczema

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5
Q

what is discoid eczema?

A

in annular discs,

mimics psoriasis and tinea

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6
Q

discoid eczema responds to?

A

potent topical steroids

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7
Q

what is asteatotic eczema? where? who? when

A

front of legs of elderly in winter

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8
Q

how does pompholyx/vesicular hand/foot eczema happen?

A

excessive washing/sweating

avoid soaps

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9
Q

what is diffuse erythrodermic eczema?

A

> 90% body eczema

treat with systemic immunosuppression

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10
Q

eczema has golden crust around it, what is it probably?

A

staph aureus colonized the eczema

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11
Q

treatments for staph aureus in eczema?

A

chlorine bath

systemic antibiotics

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12
Q

eczema herpeticum is? looks like

A

secondary infection by HSV

punched out erosions

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13
Q

why is eczema herpeticum medical emergency? how treat?

A

corneal scarring

systemic antivirals

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14
Q

how to diagnose contact dermatitis?

A

patch testing

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15
Q

how to diagnose contact dermatitis?

A

patch testing

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16
Q

what kind of phototherapy for atopic eczema?

A

UVB 311nm

immunodesensitization

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17
Q

atopic eczema immunosuppression options?

A

short: oral prednisolone

med-long: methotrexate, azathioprine etc.

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18
Q

erythematous, scaly well demarcated plaques most likely dx?

A

chronic plaque psoriasis

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19
Q

2 peaks of onset for psoriasis?

A

20s

50s

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20
Q

where get rash in psoriasis?

A

extensor rash

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21
Q

psoriasis appearance classical?

A
symmetrical
extensor surface
scaly
well demarcated
erythematous
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22
Q

most common cause of eruption on penis is?

A

genital psoriasis

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23
Q

nail psoriasis can cause what to nail?

A

onycholysis

24
Q

what is guttate psoriasis? who gets it? trigger?

A

‘raindrop’ psoriasis
kids
triggered 1-2/52 post strep infections, URTI

25
Q

how to treat guttate psoriasis?

A

phototherapy

26
Q

pustular psoriasis dangerous?

A

yes. medical emergency

systemic fever, chills, loss of barrier function

27
Q

psoriatic arthritis affects how many % of psoriasis patients?

A

10%

28
Q

systemic Rx of psoriatic arthritis

A

methotrexate, cyclosporin A, biologics

29
Q

Acne is disorder of what structure?

A

pilosebaceous unit

30
Q

acne influences by genetics?

A

strongly

31
Q

acne influences by genetics?

A

strongly

32
Q

4 components of acne?

A
  1. keratinization of sebaceous duct
  2. bacteria colonization
  3. increase androgen levels
  4. inflammation
33
Q

what bacteria causes acne?

A

propionobactrium acnes

34
Q

comedones are made of what?

A

oxidized sebum

35
Q

whiteheads and black heads are?

A

whiteheads: closed comedones
blackheads: open comedones

36
Q

whiteheads and black heads are?

A

whiteheads: closed comedones
blackheads: open comedones

37
Q

mild-mod inflammatory lesions of acne are?

A

papules

pustules

38
Q

severe acne called?

A

acne conglobata

39
Q

adult onset acne in female if has androgenisation, alopecia, consider what?

A

PCOS

40
Q

describe acne scars

A

textural change is permanent

colour is treatable

41
Q

what meds get rid of comedones?

A

keratolytics

comedolytics

42
Q

what topical Abx in acne?

A

erythromycin

clindamycin

43
Q

what systemic ABx in acne?

A

doxy
minocycline
erythromycin
trimethoprim

44
Q

big contraindication for systemic isotretinoin?

A

teratogenic

45
Q

systemic isotretinoin treatment course?

A

6-12 months

46
Q

Rosacea has 2 components:

A

vascular reactivity

inflammatory papules and pustules

47
Q

difference between Rosacea and acne?

A

no comedones

48
Q

long term: complication of Rosacea in men

A

Rhinophyma: sebaceus hyperplasia

49
Q

ocular Rosacea happens to who?

A

20-40% of ppl with cutaneous Rosacea

50
Q

scabies danger?

A

very contagious

51
Q

scabies danger in indigenous?

A

predispose to staph and strep: rheumatic fever

52
Q

scabies danger in indigenous?

A

predispose to staph and strep: rheumatic fever

53
Q

symptoms of scabies?

A

intensely itchy, starts in hands then spreads

54
Q

how long does it take for itch to come on first time you get scabies? second time?

A

first: about a month
second: immediately

55
Q

3 things to confirm dx of scabies under microscope?

A

egg
scabies mite
faeces

56
Q

first line Rx for scabies?

A

5% permethrin cream leave on overnight, wash off in AM,

57
Q

treat who in scabies?

A

all contacts

wash everything