Dermatology II Flashcards

1
Q

where does atopic eczema usually occur? look like?

A

ill defined
scaly
patches
in flexures

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2
Q

what is filaggrin mutation?

A

genetic reduced skin barrier function, more likely atopic eczema

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3
Q

atopic eczema happens where on infant more likely?

A

face

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4
Q

what is lichenification?

A

chronic rubbing/scratching of atopic eczema

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5
Q

what is discoid eczema?

A

in annular discs,

mimics psoriasis and tinea

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6
Q

discoid eczema responds to?

A

potent topical steroids

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7
Q

what is asteatotic eczema? where? who? when

A

front of legs of elderly in winter

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8
Q

how does pompholyx/vesicular hand/foot eczema happen?

A

excessive washing/sweating

avoid soaps

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9
Q

what is diffuse erythrodermic eczema?

A

> 90% body eczema

treat with systemic immunosuppression

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10
Q

eczema has golden crust around it, what is it probably?

A

staph aureus colonized the eczema

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11
Q

treatments for staph aureus in eczema?

A

chlorine bath

systemic antibiotics

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12
Q

eczema herpeticum is? looks like

A

secondary infection by HSV

punched out erosions

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13
Q

why is eczema herpeticum medical emergency? how treat?

A

corneal scarring

systemic antivirals

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14
Q

how to diagnose contact dermatitis?

A

patch testing

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15
Q

how to diagnose contact dermatitis?

A

patch testing

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16
Q

what kind of phototherapy for atopic eczema?

A

UVB 311nm

immunodesensitization

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17
Q

atopic eczema immunosuppression options?

A

short: oral prednisolone

med-long: methotrexate, azathioprine etc.

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18
Q

erythematous, scaly well demarcated plaques most likely dx?

A

chronic plaque psoriasis

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19
Q

2 peaks of onset for psoriasis?

A

20s

50s

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20
Q

where get rash in psoriasis?

A

extensor rash

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21
Q

psoriasis appearance classical?

A
symmetrical
extensor surface
scaly
well demarcated
erythematous
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22
Q

most common cause of eruption on penis is?

A

genital psoriasis

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23
Q

nail psoriasis can cause what to nail?

A

onycholysis

24
Q

what is guttate psoriasis? who gets it? trigger?

A

‘raindrop’ psoriasis
kids
triggered 1-2/52 post strep infections, URTI

25
how to treat guttate psoriasis?
phototherapy
26
pustular psoriasis dangerous?
yes. medical emergency | systemic fever, chills, loss of barrier function
27
psoriatic arthritis affects how many % of psoriasis patients?
10%
28
systemic Rx of psoriatic arthritis
methotrexate, cyclosporin A, biologics
29
Acne is disorder of what structure?
pilosebaceous unit
30
acne influences by genetics?
strongly
31
acne influences by genetics?
strongly
32
4 components of acne?
1. keratinization of sebaceous duct 2. bacteria colonization 3. increase androgen levels 4. inflammation
33
what bacteria causes acne?
propionobactrium acnes
34
comedones are made of what?
oxidized sebum
35
whiteheads and black heads are?
whiteheads: closed comedones blackheads: open comedones
36
whiteheads and black heads are?
whiteheads: closed comedones blackheads: open comedones
37
mild-mod inflammatory lesions of acne are?
papules | pustules
38
severe acne called?
acne conglobata
39
adult onset acne in female if has androgenisation, alopecia, consider what?
PCOS
40
describe acne scars
textural change is permanent | colour is treatable
41
what meds get rid of comedones?
keratolytics | comedolytics
42
what topical Abx in acne?
erythromycin | clindamycin
43
what systemic ABx in acne?
doxy minocycline erythromycin trimethoprim
44
big contraindication for systemic isotretinoin?
teratogenic
45
systemic isotretinoin treatment course?
6-12 months
46
Rosacea has 2 components:
vascular reactivity | inflammatory papules and pustules
47
difference between Rosacea and acne?
no comedones
48
long term: complication of Rosacea in men
Rhinophyma: sebaceus hyperplasia
49
ocular Rosacea happens to who?
20-40% of ppl with cutaneous Rosacea
50
scabies danger?
very contagious
51
scabies danger in indigenous?
predispose to staph and strep: rheumatic fever
52
scabies danger in indigenous?
predispose to staph and strep: rheumatic fever
53
symptoms of scabies?
intensely itchy, starts in hands then spreads
54
how long does it take for itch to come on first time you get scabies? second time?
first: about a month second: immediately
55
3 things to confirm dx of scabies under microscope?
egg scabies mite faeces
56
first line Rx for scabies?
5% permethrin cream leave on overnight, wash off in AM,
57
treat who in scabies?
all contacts | wash everything