Infection Flashcards

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1
Q

واکسن‌های زنده ضعیف شده

A

BOY IS MR

BCG    سل
OPV    فلج اطفال
Yellow fever
Influenza
Salmonella
MMR

❌ Don’t give to low immune

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2
Q

Tricomaniasis ttt?

A

Metronidazole

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3
Q

Vesicular oral lesion dx?

A

Herpes simplex

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4
Q

Meningitis CSF: high pro/ low glu/ high WBC polymorph 70%

DDx?

A

Bacterial

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5
Q

TB انتقال

A

Droplet

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6
Q

Painful ex genital ulcer Dx

A

Genital herpes

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7
Q

Dengue fever cause?

symp (8)?

A

Dengue virus is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes of the virus have been found, a reported fifth has yet to be confirmed, all of which can cause the full spectrum of disease

Yellow fever is spread by the bite of infected Aedes aegypti mosquitoes. A mosquito becomes infected when it bites a person who has yellow fever in his or her blood

Sepik virus. Tembusu virus. Tick-borne encephalitis virus. Tyuleniy virus.

Sudden, high fever.
Severe headaches.
Pain behind the eyes.
Severe joint and muscle pain.
Fatigue.
Nausea.
Vomiting.
Skin rash, which appears two to five days after the onset of fever.
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8
Q

Impetigo ttt

A

Oral antibiotic therapy can be used for impetigo with large bullae or when topical therapy is impractical. Amoxicillin/clavulanate, dicloxacillin, cephalexin, clindamycin, doxycycline, minocycline, trimethoprim/sulfamethoxazole, and macrolides are options, but penicillin is not❌

Impetigo is treated with antibiotics that are either rubbed onto the sores (topical antibiotics) or taken by mouth (oral antibiotics). A doctor might recommend a topical ointment, such as mupirocin or retapamulin, for only a few sores. Oral antibiotics can be used when there are more sores

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9
Q

Scabies (also known as the seven-year itch)

A

جرب

Sarcoptes scabiei or the itch mite is a parasitic mite that burrows into skin and causes scabies

Scabies signs and symptoms include: Itching, often severe and usually worse at night.
Between the fingers.
In the armpits.
Around the waist.
Along the insides of the wrists.
On the inner elbows.
On the soles of the feet.
Around the breasts.
Around the male genital area.
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10
Q

Herpangina

A

“mouth blisters”/ painful mouth infection/ coxsackieviruses/ Usually coxsackie virus A “herpangina virus” > coxsackievirus B or echoviruses/summer/ mostly children

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11
Q

Croup

A

Croup refers to an infection of the upper airway, which obstructs breathing and causes a characteristic barking cough. The cough and other signs and symptoms of croup are the result of swelling around the voice box (larynx), windpipe (trachea) and bronchial tubes (bronchi).

Croup is usually caused by a viral infection, most often a parainfluenza virus. Your child may contract a virus by breathing infected respiratory droplets coughed or sneezed into the air. Virus particles in these droplets may also survive on toys and other surfaces

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12
Q

Leprosy ttt

A

Hansen’s diseas
جذام

treated with a combination of antibiotics. Typically, 2 or 3 antibiotics are used at the same time. These are (1)dapsone with (2)rifampicin, and (3)clofazimine is added for some types of the disease. This is called multidrug therapy.

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13
Q

Macule, papule, pustule, vesicule, rash in same time?

A

Varicella zoster

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14
Q

Aspergelloma

A

An aspergilloma is a fungus ball or mycetoma composed of Aspergillus hyphae along with cellular debris and mucus. It is a noninvasive type of chronic pulmonary aspergillosis. Aspergillus species colonize the preexisting cavity in the lung parenchyma and form a fungus cavity

CT: saprophytic aspergillosis (aspergilloma) is characterized by a mass with soft-tissue attenuation within a lung cavity. The mass is typically separated from the cavity wall by an airspace (“air crescent” sign) and is often associated with thickening of the wall and adjacent pleura

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15
Q

Legionella pneumophila symp

A

The symptoms of Legionnaires’ disease are similar to the symptoms of the flu:
high temperature, feverishness and chills;
cough;
muscle pains;
headache; and leading on to.
pneumonia, very occasionally.
diarrhoea and signs of mental confusion.

Legionnaires’ disease is a type of pneumonia caused by bacteria. You usually get it by breathing in mist from water that contains the bacteria. The mist may come from hot tubs, showers, or air-conditioning units for large buildings. The bacteria don’t spread from person to person

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16
Q

How do you know if you have Legionella dis (legionnaires)? Ttt?

A

The most commonly used laboratory test for diagnosis of Legionnaires’ disease is the urinary antigen test (UAT), which detects a molecule of the Legionella bacterium in urine. If the patient has pneumonia and the test is positive, then you should consider the patient to have Legionnaires’ disease

Azithromycin is the drug of choice for children with suspected or confirmed Legionella disease

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17
Q

Discharge, gram - diplococci

A

Gonorrha

nucleic acid amplification test +

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18
Q

Giardia

A

Giardia duodenalis, also known as Giardia intestinalis and Giardia lamblia, is a flagellated parasitic microorganism of the genus Giardia that colonizes the small intestine, causing a diarrheal condition known as giardiasis.

The parasite attaches itself to the lining of the small intestines in humans, where it causes diarrhea and interferes with the body’s absorption of fats and carbohydrates from digested foods /❌ not invasive

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19
Q

STD painless ulcer, elevated margins, inguinal lymph nodes enlarged

A

Syphilis is caused by Treponema pallidum

The disease starts as a painless sore — typically on the genitals, rectum or mouth. Syphilis spreads from person to person via skin or mucous membrane contact with these sores

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20
Q

Blue inclusion in smear of witch malaria

A

Falciparium

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21
Q

Most cases of mother-to-child transmission of HIV

A

occur during labour. As with sexual transmission, R5-tropic viruses are more likely to be transmitted from mother to child. The mechanisms underlying these observations are not completely defined. The overall risk of vertical transmission of HIV is 25-30%

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22
Q

HPV symp

A

Human papilloma virus
It is usually spread through vaginal, oral, or anal sex. Many women do not know they have HPV, because it usually has no symptoms and usually goes away on its own. Some types of HPV can cause illnesses such as genital warts or cervical cancer. There is a vaccine to help you prevent HPV.

HPV can infect cells in the vagina and around the vulva. If a female has low risk HPV, they may see warts on the vulva. These warts may present as: a cluster that looks like a cauliflower.گل‌کلم

Some symptoms of vaginal cancer include :
bleeding after sex.
unusual discharge.
a lump in the vagina.
pain while having sex.

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23
Q

UTI common bacteria

A

E.coli

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24
Q

Itching vagina, cheesy discharge?

ttt?

A

Candidiasis

Vaginal candidiasis is usually treated with antifungal medicine. For most infections, the treatment is an antifungal medicine applied inside the vagina or a single dose of fluconazole taken by mouth

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25
Q

Mumps complication

A

Orchitis (or-KIE-tis) is an inflammation of one or both testicles. Bacterial or viral infections can cause orchitis, or the cause can be unknown. Orchitis is most often the result of a bacterial infection, such as a sexually transmitted infection (STI). In some cases, the mumps virus can cause orchitis

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26
Q

Best investigation for sinusitis

A

CT

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27
Q

Abscess sign? ttt?

A

Tender, warm, fluctuated

Incisional and drainage

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28
Q

Who gets varicella immunoglobulin? IVIG

A

Varicella-zoster immune globulin is used to prevent exposure of varicella virus in high risk individuals, (1)such as adults and children with weakened immune system, (2)pregnant women, (3)premature babies, and (4)babies younger than 1 year of age

VariZIG is now approved for administration as soon as possible following varicella-zoster virus exposure, ideally within 96 hours (4 days) for greatest effectiveness. CDC recommends administration of VariZIG as soon as possible after exposure to the varicella-zoster virus and within 10 days

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29
Q

Cause of AB use in acne vulgaris

A

Prevent physical scar formation

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30
Q

Bitten by a cat, organism?

A

Pasteurella Multocida

31
Q

pustular folliculitis scalp

A

Scalp folliculitis is an inflammatory disorder of the hair follicles in the scalp. The condition is also known as “acne necrotica miliaris” or “Proprionibacterium folliculitis”. Scalp folliculitis is characterised by small, very itchy pustules on the scalp, often most troublesome on the frontal hairline

Resist the temptation to squeeze or pop a folliculitis boil. While you might manage to express the pus and other infected fluid, you also run the risk of pushing those toxins more deeply into the skin, to the point that they may enter your bloodstream. Instead, let your dermatologist diagnose and treat the problem

32
Q

Treatment for scalp folliculitis includes (6)

A
  1. Topical antibiotics. Clindamycin solution. …
  2. Topical steroid creams or lotions.
  3. Oral antihistamines.
  4. Oral antibiotics, particularly long-term tetracycline.
  5. Oral isotretinoin. …
  6. Antidandruff shampoos containing antifungal agents such as ketoconazole or ciclopirox may be helpful.
33
Q

Syphilis bac

A

Treponema pallidum is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only amongst humans. It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide

34
Q

ASO titer

A

Antistreptolysin O (ASO) titer is a blood test to measure antibodies against streptolysin O, a substance produced by group A streptococcus bacteria. Antibodies are proteins our bodies produce when they detect harmful substances, such as bacteria

you may need to repeat the ASO titer 2 weeks after your first blood sample

Positive ASO test confirms past infection; thus it’s useful to support the diagnosis of the poststreptococcal illness when it’s suspected, like poststreptococcal glomerulonephritis, pediatric autoimmune neuropsychiatric disorders associated with streptococcus (PANDAS), and rheumatic fever

test value below 200 is considered normal. In children under the age of 5, the test value should be less than 100

35
Q

Eikenella corrode

A

Eikenella corrodens and group A streptococcal infections are rarely associated with dog bites. They are constituents of normal human mouth flora and often are associated with human bites. Most dog bites to young children occur in the home

In adults, Eikenella species have been shown to cause head and neck infection, sinusitis, pulmonary infection, arthritis, endocarditis, intraabdominal infection, pancreatic abscesses, skull infection, vertebral osteomyelitis, and infection after human bite wounds

36
Q

HIV purpule lesion on the body and oral cavity

A

Kaposi’s Sarcoma and HIV/AIDS
It occurs among people who have HIV/AIDS. It is related to a herpes type virus. KS appears as purplish or dark lesions on the skin. Because of the weakened immune system caused by AIDS, KS can spread quickly to other parts of the body, including internal organs

It can usually be treated very effectively by taking HIV medicine known as combination antiretroviral therapy (cART). This prevents HIV multiplying and allows the immune system to recover.

37
Q

Vibrio cholera ttt?

Prophilaxis

A

Oral or intravenous hydration is the primary treatment for cholera. In conjunction with hydration, treatment with antibiotics is recommended for severely ill patients. It is also recommended for patients who have severe or some dehydration and continue to pass a large volume of stool during rehydration treatment.

Several antibiotics are effective in the treatment of cholera, including doxycycline, tetracyclin, ciprofloxacin, and azithromycin, assuming that the cholera strain is sensitive

The FDA approved a single-dose live oral cholera vaccine called Vaxchora®. Vaxchora is recommended to prevent infection in adults who are 18 – 64 years old and are traveling to an area of active cholera transmission with toxigenic Vibrio cholerae O1 (the bacteria strain that most commonly causes cholera).

38
Q

Tinea capitis

A

Tinea capitis, or scalp ringworm, is a fungal infection that affects your child’s scalp and hair. Symptoms of tinea capitis include swollen red patches, dry scaly rashes, itchiness and hair loss. Mold-like fungi called dermatophytes cause tinea capitis.
Scaly hair loss in border o hair growing

39
Q

Herpes zoster treatment guidelines

A

Adults with herpes zoster can be treated with oral acyclovir at a dose of 800 mg five times daily. The recommended dose of intravenous acyclovir for VZV infections is 10 mg/kg every 8 hours, although higher doses (12–15 mg/kg) are sometimes used for life-threatening infections, especially in immunocompromised patients

40
Q

pneumocystis carinii infection

A

Pneumocystis carinii is a common cause of pneumonia in individuals who are immunosuppressed by HIV infection. Use of molecular biological techniques show that P. carinii is a fungus and that infection in man is not a zoonosis. Invasive tests such as sputum induction or bronchoscopy are used to make the diagnosis of P.

Pneumocystis jiroveci pneumonia is a fungal infection of the lungs. The disease used to be called Pneumocystis carini or PCP pneumonia

Pneumocystis pneumonia (PCP)

41
Q

molluscum contagiosum

A

Molluscum contagiosum is a sexually transmitted infection (STI) in adults as it can be spread by skin-to-skin contact during sex. It’s characterised by small, smooth, round, pearly lumps with a central core. The infection usually resolves itself, but treatment can shorten the length of symptoms

Molluscum contagiosum is caused by a virus in the poxvirus family. This is different from the human papilloma virus (HPV) family that causes warts, but these two conditions are commonly discussed together because they are contagious viral diseases that cause skin lesions

creams that contain iodine and salicylic acid or potassium hydroxide. trichloroacetic acid. topical podophyllotoxin cream (Condylox) cantharidin (Cantharone), a blistering agent that a doctor usually applies

42
Q

Infectious mononucleosis

A

Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). Most people are infected by the virus as children, when the disease produces few or no symptoms.

43
Q

Child with pharyngititis during abd examination became pale and hypotensive

A

Splenic rupture is a rare but life-threatening complication of Epstein-Barr Virus (EBV)-induced infectious mononucleosis (IM). It occurs in less than 0.5% of cases, with as many as 86% of those cases occurring spontaneously or atraumatically. It is the most frequent cause of death in IM.

Mononucleosis may cause enlargement of the spleen. The mechanism of splenic rupture secondary to infectious mononucleosis has been controversial. It is commonly believed that it is caused by an increase in intra-abdominal pressure or contraction of the diaphragm with vigorous cough, vomiting and defecation, leading to a compression of the spleen.

44
Q

Why does the flu vaccine have to change every year?

A

It’s because new strains of the virus are constantly appearing and evolving, so the vaccine must change along with them. Located around the world are influenza surveillance centers that annually monitor the most common strains, collecting data and identifying new and evolving strains

Influenza viruses constantly change through a process called antigenic drift. This is the random accumulation of mutations in the haemagglutinin (HA), and to a lesser extent neuraminidase (NA) genes, recognized by the immune system. It is most pronounced in influenza A viruses

45
Q

Erysipelas

A

باد سرخ
is an infection of the upper layers of the skin (superficial). The most common cause is group A streptococcal bacteria, especially Streptococcus pyogenes. Erysipelas results in a fiery red rash with raised edges that can easily be distinguished from the skin around it.

is usually diagnosed by the clinician looking at the characteristic well-demarcated rash following a history of injury or recognition of one of the risk factors. Tests, if performed, may show a high white cell count, raised CRP or positive blood culture identifying the organism.

46
Q

پروفیلاکسی مننژیت در کادر درمان

A

تنها نوع مننژیت که در شرایط خاص نیاز به دریافت پروفیلاکسی برای پرسنل حرف پزشکی دارد مننژیت مننگوکوکی است که خوشبختانه شایع نیست و امروزه کمتر با آن مواجه می شویم:
در صورتیکه تنفس دهان به دهان و یا اینتوباسیون توسط پزشک یا پرستار برای بیمار انجام شود نیاز به پروفیلاکسی بدنبال مواجهه با مننژیت مننگوکوکی خواهند داشت که شامل ریفامپین ۲600mg بار در روز برای 2 روز یا تک دوز سیپروفلوکساسین 500mg و یا تک دوز سفتریاکسون 250mg عضلانی، در غیر اینصورت نیاز به پروفیلاکسی نخواهد بود.
در بیمار مبتلا به مننژیت مننگوکوکی 24 ساعت پس از دریافت آنتی بیوتیک مناسب می تواند از ایزولاسیون خارج شود.

47
Q

Ulcer in mouth, margine well demarcated and red, floor yellow, superficial, very painfull

A

Canker sores, also called aphthous ulcers, are small, shallow lesions that develop on the soft tissues in your mouth or at the base of your gums. Unlike cold sores, canker sores don’t occur on the surface of your lips and they aren’t contagious. They can be painful, however, and can make eating and talking difficult

Aphthous ulcers are recurring ulcers which affect around 20 per cent of the population. Although in most people there is no known cause for aphthous ulcers, in a small number of people these ulcers may be due to an underlying Vitamin B, folate or iron deficiency

48
Q

Vomiting after 4 or 6 hour after eating

A

Staph aureous

49
Q

Leishmania

A

Leishmania is a parasitic protozoan, a single-celled organism of the genus trypanosomes that are responsible for the disease leishmaniasis. They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World

There are several different forms of leishmaniasis in people. The most common forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow).

50
Q

Leishmaniasis ttt

A

The only Food and Drug Administration (FDA)-approved medications for the treatment of leishmaniasis are intravenous liposomal amphotericin B (L-AmB) for VL and oral miltefosine for CL, ML, and VL caused by particular species

51
Q

Which f the following methods can be used to removed Entamoeba histolytica cysts in contaminated drinking water?

A

histolytica cysts can be efficiently captured and removed from contaminated aqueous systems through the application of synthesized nanoparticles.

52
Q

Entamoeba histolytica

A

Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. E. histolytica infection is estimated to kill more than 55,000 people each year

E histolytica can live in the large intestine (colon) without causing damage to the intestine. In some cases, it invades the colon wall, causing colitis, acute dysentery, or long-term (chronic) diarrhea. The infection can also spread through the bloodstream to the liver

53
Q

Plauge

A

طاعون
Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.

Remove brush, rock piles, junk, cluttered firewood, and possible rodent food supplies, such as pet and wild animal food. Make your home and outbuildings rodent-proof. Wear gloves if you are handling or skinning potentially infected animals to prevent contact between your skin and the plague bacteria.
Kill rodents to prevent

54
Q

You can take these steps to reduce your risk of MRSA infection:

A

Maintain good hand and body hygiene. …
Keep cuts, scrapes, and wounds clean and covered until healed.
Avoid sharing personal items such as towels and razors.
Get care early if you think you might have an infection.

55
Q

How often do you need your varicella vaccine?

A

CDC recommends two doses of chickenpox vaccine for children, adolescents, and adults. Children should receive two doses of the vaccine—the first dose at 12 through 15 months old and a second dose at 4 through 6 years old

Anyone who hasn’t gotten chickenpox should get the chickenpox vaccine. Older children and adults can get it at any time. Older children and adults should receive two doses at least 28 days apart if they’ve never had chickenpox or received the chickenpox vaccine.

56
Q

Brucellosis

A

Brucella is a genus of Gram-negative bacteria, named after David Bruce. They are small, nonencapsulated, nonmotile, facultatively intracellular coccobacilli

People with brucellosis may develop fever, sweats, headaches, back pains, and physical weakness. In severe cases, the central nervous system and the lining of the heart may be affected. One form of the illness may also cause long-lasting symptoms, including recurrent fevers, joint pain, and fatigue.
تب مالت

57
Q

Maculopapular rash ddx

A

Infectious processes that should be considered in the dif- ferential diagnosis of maculopapular rashes include viruses (1measles, 2rubella, 3HHV-6, 4parvovirus B19, 5enterovirus, 6Epstein-Barr virus, 7adenovirus, 8dengue fever) and bacteria (Streptococcus pyogenes)

58
Q

Measles

A

سرخک

59
Q

Rubella

A

سرخجه

60
Q

Mumps

A

اوریون

61
Q

Varicella

A

آبله مرغان

62
Q

When use steroid in TB

A

Corticosteroids are often used as an adjunct in the treatment of various forms of tuberculosis (TB) and for the prevention of complications, such as constrictive pericarditis, hydrocephalus, focal neurological deficits, pleural adhesions, and intestinal strictures.

Use of corticosteroids in conjunction with antituberculous therapy showed a reduction in mortality and morbidity in pericardial and central nervous system TB. Signs and symptoms in pleural and severe pulmonary TB improve rapidly with the addition of corticosteroids

63
Q

Chlamydia

A

Chlamydia trachomatis is primarily a sexually transmitted infection, which can cause a distinctive pneumonia in infants born to women with active genital infection. • Chlamydia psittaci is the causative agent of psittacosis, which is usually acquired from exposure to sick birds.

chlamydia usually causes no symptoms. In addition, chlamydia can cause serious long-term complications in women who are not treated

pain or burning while peeing.
pain during sex.
lower belly pain.
abnormal vaginal discharge (may be yellowish and have a strong smell)
bleeding between periods.
pus or a watery/milky discharge from the penis.
swollen or tender testicles.

64
Q

Chlamydia ttt

A

Chlamydia can usually be effectively treated with antibiotics. More than 95% of people will be cured if they take their antibiotics correctly.
doxycycline – taken every day for a week.
azithromycin – one dose of 1g, followed by 500mg once a day for 2 days.

65
Q

Scarlet fever

A

مخملک
Scarlet fever is a bacterial illness that develops in some people who have strep throat. Also known as scarlatina, scarlet fever features a bright red rash that covers most of the body. Scarlet fever almost always includes a sore throat and a high fever. Scarlet fever is most common in children 5 to 15 years of age

Scarlet fever is usually treated with a 10-day course of antibiotics. This is often in the form of penicillin or amoxicillin tablets, although liquid may be used for young children. For people who are allergic to penicillin, alternative antibiotics such as erythromycin can be used instead

66
Q

meningitis prophylaxis

A

Close contacts of a person with meningococcal disease should receive antibiotics to prevent them from getting sick. Experts call this prophylaxis. Examples of close contacts include: People in the same household

67
Q

What is the first-line treatment for strep throat?

A

Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Prevention) “There has never been a report of a clinical isolate of group A strep that is resistant to penicillin”

68
Q

Pneumococcal vaccin indication

A

The CDC recommends the pneumococcal vaccine for adults ages 65 and older and for adults younger than 65 who have health conditions such as liver disease, HIV, asthma or diabetes.

69
Q

Absolute eosinophilia cause

A

Parasite

70
Q

LGV

A

Lymphogranuloma venereum (LGV) is a sexually transmitted disease (STD). The first stage of LGV causes genital blisters. The second stage of LGV leads to swollen, painful lymph nodes in your groin, pelvis or rectum. Antibiotics can usually treat LGV, but untreated LGV can cause long-term damage to your lymphatic system

LGV is a sexually transmitted disease (STD) or infection involving the lymph glands in the genital area. It is caused by a specific strain of Chlamydia

71
Q

Nucleic acid test

A

A nucleic acid test is a technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species or subspecies of organism, often a virus or bacterium that acts as a pathogen in blood, tissue, urine, etc

72
Q

False negative HIV

A

False negative results most often occur when people test in the first few weeks after infection, during the ‘window period’. After this, they are extremely rare. In most settings, the probability of a negative result being accurate is over 99.9%

Received an HIV-negative test result on a baseline HIV test for an incident of possible HIV exposure in the past 72 hours; in this case, and if PEP has not been initiated, re-test at 4 weeks after exposure, and if the results are still negative or discordant, the person should be re-tested again at 12 weeks after

73
Q

Rotavirus

A

Rotavirus is a genus of double-stranded RNA viruses in the family Reoviridae. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five.