Immunology

Question 1

What type of cells express Class 1 HLA on cell surface?

Answer 1

All nucleated cells

Question 2

What class of cells is expressed on specialised antigen presenting cells?

Answer 2

Class 2

Question 3

What type of hypersensitivity reaction is SLE?

Answer 3

Type 3

Question 4

What type of antibody is associated with SLE

Answer 4

ANA

Question 5

What does speckled antibody suggest?

Answer 5

SLE and Sjogrens- Ro and La

Question 6

What is associated with the anti centromere antibody

Answer 6

Systemic sclerosis

Question 7

What is associated with anti Jo

Answer 7

polymyositis, dermatomyositis

Question 8

What is associated with mixed connective tissue disease and SLE?

Answer 8

Anti RNP

Question 9

What is anti Sm associated with?

Answer 9

SLE

Question 10

What does SOAPBRAIN MD stand for?

Answer 10

seositis, oral ulcers, arthritis, photosensitivity, blood disorders, renal involvement, antinuclear antibodies, immunological phenomena, neurological disorder, malar rash and discoid rash

Question 11

How would you treat a type 3 hypersensitivity reaction

Answer 11

corticosteroids for inflam and then immunosuppressive agents

Question 12

What geological test would you use in rheumatoid arthritis only?

Answer 12

rheumatic factor AND ANTI CCP