Drug side effects

Question 1

what is th major side effect in paracetamol

Answer 1

overdose toxicity

Question 2

what major problems does NSAIDS cause

Answer 2

dyspepsia, oesophagitis, gastritis, N and V, peptic ulcer, bowel ulceration, renal impairment, fluid retention, rash, increase in CV events

Question 3

what are methotrexate side effects

Answer 3

thrombocytopenia, leucopenia, nausea and diarrhoea, hepatitis/ cirrhosis, rash, tetragenic, pneumonitis

Question 4

what are sulphasalazine AE

Answer 4

oligozoospermia, neutropenia, rash/ mouth ulcers, hepatitis, nausea

Question 5

what are SE of hydroxychloroquine

Answer 5

retinopathy

Question 6

what are AE of penicillamine/ gold

Answer 6

bone marrow suppression, rash and mouth ulcers, glomerulonephritis

Question 7

what are steroid AE

Answer 7

osteoporosis, skin thinning, muscle atrophy, weight gain, diabetes, hypertension, cataract, glaucoma, fluid retention, AVN femoral head

Question 8

what are TNF AE

Answer 8

TB infection, do not use in pulmonary fibrosis or heart failure

Question 9

what does colchicine cause

Answer 9

nausea and vomiting

Question 10

what SE does allopurinol have

Answer 10

renal impairment, rash, azathioprine interaction, marrow aplasia