Immunizations Flashcards
what must you give before any vaccine?
the most up-to-date Vaccine Information Statement
what is active immunity
when a person builds their own immune response because they survived an infection or received a vaccination
what is passive immunity
when a person is immune because they transferred someone else’s immune system as in giving antibodies from a mother to child
how long after you give a live vaccine should you wait to give any antibodies?
at least 2 weeks
how long do you wait between giving a antibody product and MMR or varicella vaccines? (except zoster)
at least 3 months or up to 11 months (see the PINK book)
why are live vaccines started 12 months after birth?
cuz baby has circulated vaccines
which vaccine can be started at birth?
hep b
when to start inactivated vaccines?
2 months
can you give more than one vaccine at a time ?
YES as many as possible at one time. no contraindications in the US
in the case where you have multiple doses that need to be given for a vaccine at certain intervals, what happens if you delay the interval a little
you are just delaying more protection, but you can vaccinate them after the recommended interval.
can you decrease the time interval of multi dose vaccines?
no usually not. For high risk exposure, you may do so but usually decreasing interval doesn’t allow enough time for immune system to respond
can you give live vaccines on the same day sat the PPD test?
yes inf efact its recommended on the same day because you avoid false negatives
what if a person already got a live vaccine and you want to give them the PPD test?
you have to wait 4 weeks in order to avoid false negatives of the PPD test
what if a person already got the PPD but not the live vaccine yet?
wait 48-72 hours after until the person gets the results and then given them the live vaccine
what are the most common local SE of vaccines?
pain
swelling
redness at site injection
what are systemic adverse reactions to vaccines?
fever malaise myalgias headache loss of appetite
what is the incidence of an anaphylactic reaction to a vaccine?
1 in 500,000
what are anaphylactic reactions usually mediated by?
IgE
what to administer in case of a anaphylactic reaction
epinphrine 1:1000 IM 0.01mg/kg/dose max 0.5mg/dose
who should your report an adverse reaction for vaccines?
FDA
Vaccine Adverse Event Reporting System (VAERS)
which are contraindications to vaccination with live vaccines?
pregnancy and immunosupression
define immunosuppression
20mg daily prednisone daily for at least 14 days
or 2mg/kg x 14 days or longer
when are live vaccines contraindicated for HIV patients?
only if CD4 < 200
when can a pregnant women receive a live vaccine?
never, even 1 month before pregnancy
when can a pregnant women receive an inactivated vaccine?
whenever
what about HPV vaccine and pregnancy?
defer
what about the flu vaccine and pregnacy
yes as long as its not the live vaccine
when should a pregnant woman get her TdAP?
> 2 weeks of gestation and has not had her Tdap booster (Q 10 years)
what if you are allergic to eggs, which vaccines can you not get?
influenza
yellow fervor
if anaphylactic allergy to eggs
what if a person can eat lightly cooked eggs or only gets hives from eating egg containing foods?
can give them the Inactivated form and watch the patient for 30 minutes
is allergy to eggs contraindication to MMR vaccine
no, no logner
Which vaccines can you not get if you are allergic to gelatin or neomycin?
varicella (zostavax & varivax)
MMR
what vaccines can you not give if streptomycin , polymyxin B or neomycin allergies?
inactivated polio vaccine
who should receive the DTaP vaccine?
< 7 yo
Havrix
HepA vaccine
Vaqta
HepA vaccine
two brands of HepA vaccine
Havrix/ Vaqta
engerix-B
hepatitis b vaccine