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Board Review > ErectileDysFC > Flashcards

ErectileDysFC Flashcards

1
Q

Erectile Dysfunction Causes

A

Diseases: diabetes, HTN, heart disease, nerve damage
Hormone imbalances
Psychological issues (including stress)
Neurological illness
Drugs

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2
Q

Drugs that Cause Erectile Dysfunction

A

Blood pressure medications: especially beta blockers, clonidine, methyldopa
Antipsychotics: haloperidol, chlorpromazine, fluphenazine, thioridazone
Antidepressants: SSRIs and SNRIs
Atomoxetine
BPH Drugs: finasteride, dutasteride, silodosin
Cimetidine
Opiods
Nicotine

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3
Q

Phosphodiesterase 5 Inhibitors MOA and names of the 3

A

Following sexual stimulation, PDE5 inhibitors increase Blood flow to the penis
Sildenafil (Viagra)
Vardenafil (Levitra, Staxyn ODT)
Tadalafil (Cialis)

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4
Q

PDE5 CI and cautions

A

CI: use with nitrates
Caution with Alpha Blocker Therapy (tamsulosin, doxazosin, etc)

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5
Q

Sildenafil (Viagra) dosing ? Ddis?

Food?

A

Start at 50mg 1 hour before intercourse (25mg in elderly and CrCl <30)
Best when taken on an empty stomach, avoid with fatty food
Use lower doses if concurrent 3A4 inhibitor use

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6
Q

se of viagra

A

SE: dizziness, sudden drop in BP, headache, dyspepsia, flushing, runny nose, stomach/back pain, priapism, vision and hearing problems

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7
Q

Vardenafil (Levitra, Staxyn ODT) dosing , food guidelines and cyp 3a4 use

A

Start at 10mg 1 hour before intercourse (5mg in elderly)
Best when taken on an empty stomach, avoid with fatty food
Use lower doses if concurrent 3A4 inhibitor use

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8
Q

Tadalafil (Cialis) dosing

Ddis?

A

Start at 10mg 1 hour before intercourse or 2.55mg daily for men who use >2 times/week
Use lower doses if concurrent 3A4 inhibitor use

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9
Q

cialis , food?

A

Take with or without food

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10
Q

se cialis

A

SE: dizziness, sudden drop in BP, headache, dyspepsia, flushing, runny nose, stomach/back pain, priapism, vision and hearing problems

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11
Q

Intracavernosal Alprostadil (Caverject) how to use

A

Injected via syringe into penis

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12
Q

se of caverject

A

SE: penile pain
hematoma
priapism

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13
Q

when does caverject cuase an erection ?

A

Causes erection 510 mins after injection (max 3x/week and 1x/day)

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14
Q

how to store caverject

A

Refrigerate vials, reconstitute prior to use

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15
Q

Transurethral Alprostadil (MUSE) how to admnister

A

Inserted into urethra

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16
Q

se of alprostadile in MUSe

A

SE: penile pain

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17
Q

how to store MUSE

A

Refrigerate

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18
Q

TriMix gel (Papaverine, Phentolamine, Alprostadil) how to administer

A

Inserted into urethra, doses of 500mcg

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19
Q

se of TRIMIX

A

SE: penile pain

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20
Q

how to obtain TirMix

A

Compounded (not FDA approved)

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21
Q

caution should be used with ED drugs and what other class?

A

Alpha blocker therapy (tamsulosin, doxazosin)

22
Q

what labratory test can be used to distinguish between prostate cancer and BPH?

A

PSA prostate specific antigen is seen in prostate cancer

23
Q

what is the MOA of alpha blockers in BPH?

A

they relax smooth muscle of the prostate and bladder neck to improve urine flow.

24
Q

what are the nonselective alpha blockers?

A

terazosin (Hytrin) and doxazosin (Cardura)

25
Q

what are the selective alpha blockers?

A

tamsulosin (Flomax), alfuzosin (Uroxatral), silodosin (Rapaflo)

26
Q

what pt population should not take alfuzosin?

A

pts at risk for QT interval prolongation

27
Q

what is another brand name for finasteride other than Proscar?

A

Propecia for hair loss

28
Q

what is the prego category of the 5alpha reductase inhibitors?

A

X

29
Q

what is the MOA of the 5alpha reductase inhibitors?

A

shrink the prostate and decrease PSA levels

30
Q

what are some common medications for overactive bladder?

A

oxybutynin, tolterodine, solifenacin, darifenacin

31
Q

oxybutynin brand

A

Ditropan

32
Q

tolterodine Brand

A

Detrol

33
Q

solifenacin Brand

A

Vesicare

34
Q

darifenacin brand

A

Enablex

35
Q

what are the side effects of the overactive bladder med?

A

anticholinergic cant see, cant pee, cant spit cant shit

36
Q

What are the abbreviations for right ear, left ear, each ear?

A

AD, AS, AU

37
Q

What are the abbreviations for right eye, left eye, each eye?

A

OD, OS, OU

38
Q

suspensions require shaking prior to use?

A

yes

39
Q

what are the common Prostaglandin analogs used for glaucoma?

A

travoprost, bimatoprost, latanoprost

40
Q

travoprost Brand

A

Travatan

41
Q

bimatoprost

A

Lumigan

42
Q

Latanoprost

A

Xalatan

43
Q

what eyedrop is indicated for increase lash lenght?

A

bimatoprost (Latisse)

44
Q

which unopenede bottles needs to be refrigerated?

A

latanoprost (Xalatan)

45
Q

brimonidine brand

A

Alphagan

46
Q

azithromycin eye drops brand

A

Azasite

47
Q

moxifloxacin brand

A

Vigamox

48
Q

besifloxacin Brand

A

Besivance

49
Q

ciprofloxacin eye drops brand

A

Ciloxan

50
Q

ofloxacin brand

A

Ocuflxo

51
Q

gentamycin brand

A

Garamycin

52
Q

tobramycin brand

A

Tobrex

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