Immune-mediated Dz Questions

Question 1

An 8yo FS Labrador retriever presents for weakness and your CBC shows a platelet count of 20,000. What should you be considering?

Answer 1

ITP
25-30,000 is the cutoff

(Could be tick-borne dz or hemangiosarcoma, etc.. depends)

Question 2

Why would you give vincristine to a dog with low platelets?

Answer 2

To make the platelet number go up and increase the ability to form a clot

Question 3

Based on phenotypic testing, which of the following is true:

1. Most canine lymphomas are B type.
2. B is almost always better than T
3. Lymphoblastic is better than lymphocytic
4. Parr Test for antigen receptor rearrangement

Answer 3

1, 2, and 4

LymphoCYTIC is better than lymphoBLASTIC…

Question 4

A 7 yo FS overweight golden retriever presents for limping. On palpation, the left stifle is painful. What are your primary rule-outs (differentials) for this dog?

Answer 4

Trauma,
Infectious dz,
Ruptured cruciate (CCL… also could be meniscus, tho)

Question 5

What drugs can cause secondary IMHA?

Answer 5

Penicillins, cephalosporins, sulfonamides, methimazole, levamisole, dipyrone, chlorpromazine