Glomerular Dz Flashcards
1
Q
Where does amyloid accumulate?
A
In mesangial cells between capillaries
2
Q
How can Cushing’s or exogenous steroids increase proteinuria?
A
By increasing BP—> increase protein in urine
3
Q
Proteinuria caused by defective renal function is considered a glomerular pathology if the UPC is _____; whereas it’s a tubular pathology if the UPC is _____.
A
High;
Low
4
Q
If the UPC ratio is >8, what should we consider with regards to glomerular dz?
A
Amyloidosis!
5
Q
What will dogs with glomerular protein loss, leading to protein losing nephropathy (PLN) present with?
A
Ascites (because lots of Alb loss) and Nephrotic Syndrome:
Hypercholesterolemia, hypoalbuminemia, azotemia, metabolic acidosis
