ILAs Flashcards

1
Q

over what values is hypertension ?

A

> 140/90
confirmed with ambulatory/home: >135/85

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2
Q

most common cause of hypertension

A

primary (90%) high BP has developed on ownc

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3
Q

causes of secondary hypertension ? 2 most common ?

A

ROPED
- renal disease (common)
- cons disease/primary hyperaldosteronism (common)
- obesity
- pregnancy induced/pre eclampsia
- endocrine
- drugs (alcohol, steroids, NSAIDs, oestrogen)

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4
Q

If high BP is not responded to treatment, what should you consider ?

A

consider renal artery stenosis
(duplex US)

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5
Q

what ranges for stage 1/2/3 hypertension ?

A
  • stage 1: >140/90 (>135/85)
  • stage 2: >160/100 (>155/95)
  • stage 3: > 180/120
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6
Q

what lifestyle advice for hypertension ?

A
  • healthy diet
  • smoking cessation
  • reduce alcohol
  • reduce caffeine
  • reduce salt
  • regular exercise
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7
Q

50 year old white man hypertension. what first line drug ? who else in the category ?

A

ACEI
(<55 or T2DM (any age))

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8
Q

50 year old black man with hypertension. what first line drug? who else in this category ?

A

CCB
(>55 or black African)

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9
Q

first line hypertension managment not enough, then add what ?

A
  • consider ACEI or CCB (whichever they’re not already on)
    OR
  • Thiazide-like diuretic
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10
Q

third line hypertension Mx ?

A

ACEI + CCB + thiazide like dietetic

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11
Q

what tests would you do in a newly diagnosed patient with hypertension to ensure they do not the any end-organ damage ? (3)

A
  • fundoscopy (check for hypertensive retinopathy)
  • urine dipstick (check for renal disease, either as a cause of consequence of hypertension)
  • ECG (to check for LV hypertrophy of IHD)
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12
Q

ACEI SE ? (2)

A
  • cough
  • hyperkalaemia
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13
Q

CCB SE ? (3)

A
  • headache
  • flushing
  • ankle oedema
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14
Q

BB SE ? (3)

A
  • bronchospasm (especially in asthmatics)
  • fatigue
  • cold peripheries
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15
Q

bendoflumethiazide SE (4)

A
  • gout
  • hyppokalaemia
  • hyponatraemia
  • impaired glucose tolerance
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16
Q

what antihypertensive is first line in diabetic patients ?

A

ACEI/ARBS regardless of age

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17
Q

What drugs can contribute to idiopathic intracranial hypertension ? (5)

A
  • COCP
  • steroids
  • tetracyclines
  • retinoids
  • lithium
18
Q

what are the BP target ranges over a patient over 80 years ?

A

<150/90 (<145/85)

19
Q

describe the antibodies associated with RA ? and what their sensitivity is ?

A
  • RF (IgM): autoantibody that attacks IgG => inflam (70% of RA patients have it)
  • Anti-CCP (more specific -80-90%)
20
Q

what indicates a worse prognosis in RA ? (3)

A
  • disease activity
  • positive Ab (RF or anti-CCP)
  • erosions on xray
  • extra-acrituclar features (nodules)
21
Q

RA RF ?

A

F:M (3:1)
middle age
smoking
obesity
FHx

22
Q

RA presentation ? which joints affected ?

A

rapid of gradual: (triad) joint pain, stiffness swelling (worse with rest, improve with activity)
- MCP, PIP, wrist, MTP

23
Q

RA hand OE ?

A
  • synovial thickening => boggy feeling
  • positive squeeze test
  • z shaped deformity
  • swan neck deformity
  • boutineirs deformity
  • ulnar deviation
24
Q

name some extra articular manifestations of RA ?

A
  • sjorgrens
  • eye manifestations (keratoconjunctivitis sick - dry eyes)
  • nodules
25
what would be seen on Xray of RA ? (5)
- periarticular osteopenia - bony erosions - soft tissue swelling - loss of joint space - subluxation
26
RA Mx ?
- short term steroids: at initial px or during flares - DMARDS: methotrexate, hydroxychloroquine/sulfasalazine (safest during pregnancy)
27
when should methotrexate be stopped prior to conception ?
6 months before conception (in men and women)
28
what would post-bronchodilator spirometry show in COPD
obstruction: FEV1/FVC ration less than 70% (0.7)
29
What would be seen on CXR of patient with COPD ?
- hyperinflation - bull - flat hemidiaphragm
30
What general lifestyle managment is recommended to patients with COPD ?
- smoking cessation - annula flu vaccine - one-off pneumococcal vaccine - pulmonary rehab
31
What is first line medical Mx of COPD ?
short-acting beta2-agonist (SABA) or short-acting muscarinic antagonist (SAMA)
32
COPD patient is not controlled on SABA. what would you consider next ? what does this depend on ?
depends on if asthmatic features suggestion steroid responsiveness - no asthmatic features: add LABA and LAMA - asthmatic features: add LABA + ICS
33
what are the features of cor pulmonale ?
- peripheral oedema - raised JVP - systolic parasternal heave - Loud P2
34
which COPD patients should be considered for Long term oxygen therapy (LTOT) ?
- severe airflow obstruction: FEV1 < 30%) - cynaosis - polycythaemia - raised JVP - Oxy sats <92%
35
most common infective causes of COPD exacerbation ?
- haemophiliac influenza (most common)
36
Gout most commonly affects which joint ?
1st metatarsophalangeal joint (MTP joint)
37
describe the fluid analysis of the synovial fluid in gout ? when checked ?
needle shape negatively birefringent monosodium rate crystals under polarised light - should be choked once the acne ep has settled down (2 weeks later)
38
pseudo gout joint aspiration description ?
weakly-positive birefringent rhomboid-shaped crystals
39
Gout acute managment ?
NSAIDs or colchicine
40
main colchicine side effect ?
diarrhoea
41