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IDR > IDR Block 3C > Flashcards

IDR Block 3C Flashcards

1
Q

Does Mycobacterium leprae cause a systemic infection?

A

No, causes skin and nerve problems

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2
Q

What type of Acid Fast Bacteria are associated with traumatic inoculation of bacteria under the skin?
What area are they from? What drugs can you use?

A

M. chelonae and M. abscessus fast growing
South and Central America (Doctor introduced, cosmetic surgery)
Standard Antibiotics

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3
Q

The opa proteins are specific to which Gram Negative?

They help the bacteria cross epithelial cells, endothelilal cells, and what two other locations?

A

N. Gonorrhea

Lymphocytes and Granulocytes

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4
Q

What types of cells does N. Gonorrhea infect? (think about histology)

A

Cervix/columnar cells

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5
Q

What type of augar does N. Gonorrhea grow on? Two options, which one is best? With what conditions?

A

Chocolate Agar is best, and Blood Agar

High humidity, CO2

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6
Q

What types of drugs work for N. Gonorrhea? What drugs do not work?

A

Azithromycin (macrolide) and Ceftriaxone (cephalosporin)

No: 1st generation Beta Lactams, ciprofloxacin, tetracyclines

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7
Q

What are the two methods of moving bacterial DNA that move B-lactamase genes?

A

Conjugation and Natural Transformation

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8
Q

What is the magic thing that causes Meningococcemia?

A

Lipo-oligosaccharide, a more exposed version of TLR4

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9
Q

What is a common cause of pneumonia in the eldery?
What drugs can be used/given?
What color is the sputum?

A

Over 75 crowd, Moraxella Catarrhalis
Anything that is not 1st generation Beta Lactams
White Sputum

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10
Q

Kerning’s Sign is what?
Brudzinski’s Sign is what?

What disease would cause this?

A

Cannot Straighten the leg of patient
Cannot pick up head without pulling up the patient’s knees
N. Meningitis

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11
Q

How is N. Meningitis spread, moved into a patient?

A

Upper Respiratory Tract, no symptoms via inhalation

Showers, Recycled air, dorms, barracks, and prisons

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12
Q

What gram negative bacteria is a fastidious capnophile?

A

N. Meningitis

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13
Q

Strept. Agalactaie causes what in pregnant women?

A

UTI and possible dissemination; can cause mastitis during breastfeeding

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14
Q

Strept. Agalactaie causes what in immuncompromised patients?

A

Sepsis, pneumonia, bone/joint, skin/soft tissue

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15
Q

___________ contains iron like TSI slants do, so bacteria that produce H2S (like Salmonella) grow into black colonies on these plates

A

Hektoen enteric agar

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16
Q

Haemophilus Ducreyi is a sexually transmitted infection that looks a lot like what?
It causes an ulcerated, painful lesion on the genitals that bleeds easily called what?

A

Treponema pallidum (syphilis)

Chancroid

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17
Q

What does the Pertussis toxin inhibit?

A

adenylate cyclase inhibitor

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18
Q

Interferes with PMN and monocyte function, catalyzes synthesis of cAMP, killing by inducing apoptosis?

A

ACT Adenylate Cyclase Toxin

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19
Q

What do tracheal cytotoxin and dermonecrotic toxin do?

A

Tracheal: Bind and immobilize cilia
Kill ciliated tracheal cells

Dermonecrotic: Localized Necrosis

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20
Q

What are the two adhesin proteins that bind to other cells that allow Bordetella pertussis to move into another cell?

A

Filamentous hemagglutinin and Pertactin

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21
Q

What are the four pieces that make up the acellular pertussis vaccine?

A

Pertactin, filamentous hemagglutinin, pertussis toxoid and adenylate cyclase

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22
Q

What part of bordetella pertussis is not able to be attacked in modernized scenarios?

A

Pertactin

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23
Q

During the bordetella pertussis growth, at what point is the Bacterial population the highest?

At what point does the heavy coughing take place?

A

Catarrhal

Paroxysmal

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24
Q

What are two different bacteria that make TB like symptoms?

A

Myobacterium Avium, and Rhodococcus Equi

25
Q

H. Influenzae is near what bacteria in some cultures in order to grow, what for example?

A

S. Pneumonia

26
Q

Bordet-Gengou or Regan-Lowe or other charcoal-containing agar grow what bacteria?

A

B. Pertussis

27
Q

What does the Paired Ser look for in B. Pertussis testing methods?

A

Look for IgM in the Convalescence phase

28
Q

Hepatitis B vaccine uses what surface peptide in order to make a good vaccine?

A

HBsAG peptide

29
Q

What is a pseudomonas disease that can cause pulmonary lung infection, CAUDI, white/yellow burn, smells like fresh dirt?

A

Burkholderia cepacia

also onion rot

30
Q

What is a pseudomonas disease that is immune competent patients, Meloidosis? Associated with livestock, have a high fever, chest pain, what area of the world? What is the disease and treatment?

A

Burkholderia Pseudomallei

South East Asia and Caribbean
Easily mistaken for TB

Will be pleomorphic on a gram stain

Sulfa drugs or doxycycline

31
Q

What disease is found via Middle East, North Africa, resists antibiotics, necrotic wound infections in soldiers?
What is the classic sign for the start of the infection?
What is different with the necrotizing fasciitis?

A

Acinetobacter Baumannii

orange peel, cellulitis

Hemmorhagic Bullae

32
Q

A classical triad of kidney failure, thrombocytopenia, and microangiopathic hemolytic anemia. Gram negative bacteria what could it be?
Schistocytes is what?

A

Hemolytic Uremic Syndrome, disable the ribosome

Helmet shaped RBCs

33
Q

What gram negative bacteria is positive for the urease?

What color will it turn?

A

Proteus

Pink

34
Q

E. Coli, Salmonella, and Proteus are positive for what test?
What gram negative bacteria is negative for this test?

A

Motility

Shigella is negative

35
Q

What gram negative bacteria will pass the citrate test?

What color will it turn?

A

Salmonella

Blue

36
Q

Enterobacter, Citrobacter, Morganella, Serratia, Providencia, Erwinia are also Enterobacteriaceae are what important value in the human body?

A

Immuncompromised, non-pathogenic otherwise

37
Q

What bacteria is Urease positive, Hydrogen sulfide positive, swarming motility, ferment aerobically and anaerobically, kidney stone/ uti?

A

P. Mirabilis

38
Q

K. Pneumoniae has what and will cause lobar pneumonia?

A

Capsule

39
Q

What drug should be used against Y. Pestis?

A

Macrolides and Ciprofloxacin

40
Q

What Drugs should be used against shigella?

A

Fluroquinolone, Sulf drugs/Trimethorpim

41
Q

What drug is used for Salmonella GI symptoms and Salmonella Typhi?

A

GI: nothing

Salmonella Typhi: ciprofloxacin

42
Q

Thus, unpasteurized dairy products, fruits/veggies eaten raw that are fertilized with cow manure, and undercooked chicken are foods most likely to cause __________ infections

What medications are used?

A

Campylobacter

Macrolides

43
Q

What two disease can get into a chicken’s bloodstream

A

Salmonella and Camylobacter

44
Q

What grows on TCBS?

A

Vibrio Cholerae

45
Q

What two proteins are necessary for actin remodeling from H. Pylori?

A

cagA and vacA

46
Q

What remodeling proteins are needed for Yersinia?

What remodeling proteins are needed for Shigella?

A

Yop

IpaA and IpaC

47
Q

What remodeling proteins are needed for Listeria Monocytogenes?

What remodeling proteins are needed for Salmonella?

A

ActA

Ssps

48
Q

What temperature does Campylobacter grow at, with what conditions?

A

Microaerophilic 5% 02 and 10% CO2

42 degrees C

49
Q

C. Jejuni is associated with a HSR type II reaction that causes what autoimmune disease?
Where does Guillain Barre Syndrome first appear?

A

Guillain-Barre Syndrome

distal limbs

50
Q

Chicken eggs are susceptible to what disease, but not another?

Cow manure can cause what bacterial problem (2) if food is not pasteurized?

A

Campylobacters –> no
Salmonella –> yes

Listeria and Campylobacters

51
Q

What medication is used for V. Vulnificus?

What medication is used for Camplyobacteria?

A

Macrolides/tetracyclines

Macrolide

52
Q

What is V. parahaemolyticus is found in what primarily?

A

Shellfish

53
Q

What does ampitrochous mean?

A

Flagella on each side

54
Q

What does lopotrochous mean?

A

Flagella bunch on one side

55
Q

What does peritrichous mean

A

Flagella all over via bacteria?

56
Q

What causes blood flecked, diaherra, with cramping, particularly in children?

A

Y. Enterocolitica

57
Q

What do EIEC, Salmonella, Camplyobacteria, have in common?

A

watery, blood flecked diarrhea

58
Q

Bordet-Gengou or Regan-Lowe or other charcoal-containing agar are used for what bacteria?

A

Bordetella Pertussis

IDR (13 decks)

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