ICU 2 Flashcards
Haemo
blood
Dynamic
changing movement
Haemodynamics
refers to the forces that affect the circulating blood throughout the body.
By using various catheters and transducers, we can .
continuously monitor
• Arterial Blood Pressure (via an Arterial Catheter)
• Central Venous Pressure (via a Central Venous Catheter)
• Pulmonary Artery Pressures (via a Pulmonary Artery
Catheter)
4 things that influence haemodynamics
Intravascular volume
Inotropy
Vasoactivity
Chronotropy
Intravascular volume
the amount of fluid circulating in the vasculature. This can be affected by • dehydration • diuresis • volume overload due to heart or kidney failure
Inotropy
The strength of myocardial contractions. Myocytes are
the only muscle cells which are able to vary the strength of
contraction.
Inotropy This can be affected positively by:
• exercise
• stress
• pharmaceutical agents, which increase the strength of myocardial
contractions
or negatively by :
• cardiac diseases such as heart failure, which decrease the strength
of contractions.
Vasoactivity
the expanding and contracting of blood vessels.
Vasoactivity This can be affected positively by:
certain hormones; eg: angiotensin II, epinephrine (adrenaline),
norepinephrine (noradrenaline), and vasopressin.
• vasodilators and vasoconstricting drugs
Chronotropy
involves the timing, or rate of heart contraction.
This can be affected by:
• Stress, activity (eg: flight or flight response,
• Certain medications (eg: +’ve accelerates the rate of impulse
formation in the SA node, -’ve slows down). These medications
are referred to as ‘inotropes’.
Inotropes alter the
the force and strength of
myocardial contractility & are used to regulate a patient’s heart
rate, blood pressure and the force of contraction of the heart.
Positive inotropes increase
the force of contraction of the heart,
whereas negative inotropes weaken it
inotropes can increase
increase cardiac output (CO), thereby increasing MAP and
maintaining perfusion to vital organs and tissues
Vasopressors
These are sympathomimetic drugs that mimic the effects of the
sympathetic nervous system. They cause vascular smooth muscle
vasoconstriction. They __________BP