I: Ovarian Pathology Flashcards
______: glomeruloid structure with tumor cells surrounding a vessel
Schiller-Duval body
______: resembles primary follicle, central space with secretions
Granulosa Cell Tumor
Name the Type 1 ovarian epithelial neoplasms
Endometrioid, Low-grade serous, Mucinous
Name the Type 2 ovarian epithelial neoplasms
High-grade serous
Name three protective factors for ovarian carcinoma
Full term pregnancy, lactation, oral contraceptive use
Which pathology? 50% of female malignant germ cell tumors, excellent prognosis, sheets/nests of cells with large central nuclei and clear cytoplasm; squared off nuclear contour
Dysgerminoma
Which pathology? Alpha-fetoprotein
Yolk Sac Tumor
Which pathology? Arise in young girls, malignant, immature neuroepithelium
Immature teratoma
Which pathology? Associated with NMDAR encephalopathy
Teratoma
Which pathology? Call-Exner bodies
Granulosa Cell Tumor
Which pathology? Can monitor recurrence with inhibin
Granulosa Cell Tumor
Which pathology? Chocolate Cyst
Endometriosis affecting the ovary
Which pathology? Fibroma, ascites, hydrothorax
Meig’s Syndrome
Which pathology? Hierarchical branching, tubal epithelium with ciliated columnar cells
Serous carcinoma
Which pathology? Hobnail cells
Clear cell carcinoma
Which pathology? Malignancy with psammoma bodies
Serous carcinoma
Which pathology? Metastatic gastric carcinoma, signet ring cell morphology
Krukenberg tumor
Which pathology? Most common germ cell tumor
Teratoma
Which pathology? Mucin throughout the abdominal cavity with possible epithelial cells present
Pseudomyxoma Peritoneii
Which pathology? Multiloculated cystic mass with sticky mucoid contents; basally located nuclei in glanudarl structures; invasive
Mucinous carcinoma
Which pathology? Neoplasm with crowded glands and sparse stroma
Endometrioid carcinoma
Which pathology? One or multiple thin-walled cysts without cytologic atypia or mitoses
Benign serous cystadenoma
Which pathology? Papillae with hierarchical branching, detached tufts of cuboidal epithelial cells
Serous borderline cystadenoma
Which pathology? Prominent nuclear grooves, corded growth pattern, associated with endometrial neoplasia
Granulosa Cell Tumor
Which pathology? Schiller-Duval body
Yolk Sac Tumor
Which pathology? Solid, cystic, mixed tumor; friable with hemorrhage and necrosis; complex hierarchical pattern with stromal invasion
Serous carcinoma
Which pathology? Tumors associated with poor response to radiation and chemotherapy, associated with long term survival
Borderline neoplasms
