I: Ovarian Pathology

Question 1

______: glomeruloid structure with tumor cells surrounding a vessel

Answer 1

Schiller-Duval body

Question 2

______: resembles primary follicle, central space with secretions

Answer 2

Granulosa Cell Tumor

Question 3

Name the Type 1 ovarian epithelial neoplasms

Answer 3

Endometrioid, Low-grade serous, Mucinous

Question 4

Name the Type 2 ovarian epithelial neoplasms

Answer 4

High-grade serous

Question 5

Name three protective factors for ovarian carcinoma

Answer 5

Full term pregnancy, lactation, oral contraceptive use

Question 6

Which pathology? 50% of female malignant germ cell tumors, excellent prognosis, sheets/nests of cells with large central nuclei and clear cytoplasm; squared off nuclear contour

Answer 6

Dysgerminoma

Question 7

Which pathology? Alpha-fetoprotein

Answer 7

Yolk Sac Tumor

Question 8

Which pathology? Arise in young girls, malignant, immature neuroepithelium

Answer 8

Immature teratoma

Question 9

Which pathology? Associated with NMDAR encephalopathy

Answer 9

Teratoma

Question 10

Which pathology? Call-Exner bodies

Answer 10

Granulosa Cell Tumor

Question 11

Which pathology? Can monitor recurrence with inhibin

Answer 11

Granulosa Cell Tumor

Question 12

Which pathology? Chocolate Cyst

Answer 12

Endometriosis affecting the ovary

Question 13

Which pathology? Fibroma, ascites, hydrothorax

Answer 13

Meig’s Syndrome

Question 14

Which pathology? Hierarchical branching, tubal epithelium with ciliated columnar cells

Answer 14

Serous carcinoma

Question 15

Which pathology? Hobnail cells

Answer 15

Clear cell carcinoma

Question 16

Which pathology? Malignancy with psammoma bodies

Answer 16

Serous carcinoma

Question 17

Which pathology? Metastatic gastric carcinoma, signet ring cell morphology

Answer 17

Krukenberg tumor

Question 18

Which pathology? Most common germ cell tumor

Answer 18

Teratoma

Question 19

Which pathology? Mucin throughout the abdominal cavity with possible epithelial cells present

Answer 19

Pseudomyxoma Peritoneii

Question 20

Which pathology? Multiloculated cystic mass with sticky mucoid contents; basally located nuclei in glanudarl structures; invasive

Answer 20

Mucinous carcinoma

Question 21

Which pathology? Neoplasm with crowded glands and sparse stroma

Answer 21

Endometrioid carcinoma

Question 22

Which pathology? One or multiple thin-walled cysts without cytologic atypia or mitoses

Answer 22

Benign serous cystadenoma

Question 23

Which pathology? Papillae with hierarchical branching, detached tufts of cuboidal epithelial cells

Answer 23

Serous borderline cystadenoma

Question 24

Which pathology? Prominent nuclear grooves, corded growth pattern, associated with endometrial neoplasia

Answer 24

Granulosa Cell Tumor

Question 25

Which pathology? Schiller-Duval body

Answer 25

Yolk Sac Tumor

Question 26

Which pathology? Solid, cystic, mixed tumor; friable with hemorrhage and necrosis; complex hierarchical pattern with stromal invasion

Answer 26

Serous carcinoma

Question 27

Which pathology? Tumors associated with poor response to radiation and chemotherapy, associated with long term survival

Answer 27

Borderline neoplasms