I: Female Pathology Flashcards

1
Q

Which pathology of the vulva? Painful red lesions 3-7 days after exposure; papules that become vesicles that may ulcerate

A

HSV

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2
Q

Which pathology of the vulva? Eosinophilic intranuclear inclusions, viral cytopathic effect

A

HSV

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3
Q

Cervical cancer staging is based on _______.

A

clinical factors

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4
Q

Uterin cancer staging is based on ______.

A

spread

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5
Q

Which pathology of the cervix? Dyspareunia and dysuria resulting from infection by a flagellated protozoan

A

Trichomonas

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6
Q

Which pathology of the cervix? Exophytic lesion with dilated glands and dense eosinophilic stroma

A

Cervical polyp

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7
Q

Which pathology of the cervix? Full thickness dysmaturity with infiltrating nests of cells

A

Squamous cell carcinoma

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8
Q

Which pathology of the cervix? Hyperchromasia, mucin depletion, luminal mitoses and high N:C ratio

A

Adenocarcinoma in situ

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9
Q

Which pathology of the cervix? Strawberry cervix with frothy yellow discharge

A

Trichomonas

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10
Q

Which pathology of the uterus? Adenocarcinoma associated with unopposed estrogen, obesity, and genetics

A

Endometriod adenocarcinoma

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11
Q

Which pathology of the uterus? Adenocarcinoma type that may arise from hyperplasia

A

Endometriod adenocarcinoma

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12
Q

Which pathology of the uterus? Adenocarcinoma with P53 mutations commonly

A

Serous carcinoma

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13
Q

Which pathology of the uterus? Adenocarcionoma type with PTEN and KRAS mutations commonly

A

Endometriod adenocarcinoma

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14
Q

Which pathology of the uterus? Bland smooth muscle cells with cigar-shaped nuclei

A

Leiomyoma

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15
Q

Which pathology of the uterus? Crowded glands with sparse stroma and nuclear atypia, invasive

A

Endometriod adenocarcinoma

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16
Q

Which pathology of the uterus? Endometrial glands and stroma in an extrauterine location

A

Endometriosis

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17
Q

Which pathology of the uterus? Endometrial glands and stroma in the myometrium

A

Adenomyosis

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18
Q

Which pathology of the uterus? Exophytic growth, disorganized glands out of phase with the menstrual cycle

A

Endometrial polyp

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19
Q

Which pathology of the uterus? Glandular crowding and architectural complexity, may have nuclear atypia

A

Complex Hyperplasia

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20
Q

Which pathology of the uterus? Infiltrating mass +/- hemorrhage/necrosis, most commonly metastasize to lungs

A

Leiomyosarcoma

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21
Q

Which pathology of the uterus? Larger and more aggressive type of adenocarcinoma

A

Serous carcinoma

22
Q

Which pathology of the uterus? Malignancy with epithelial and connective tissue components, heterologous tumors worsen prognosis

A

Carcinosarcoma

23
Q

Which pathology of the uterus? More common type of adenocarcinoma

A

Endometriod adenocarcinoma

24
Q

Which pathology of the uterus? Most common uterine tumor

25
Which pathology of the uterus? Occurs in post-menopausal women, adenocarcinoma
Serous carcinoma
26
Which pathology of the uterus? Occurs in pre-menopausal and perimenopausal women, adenocarcinoma
Endometriod adenocarcinoma
27
Which pathology of the uterus? Papillary growth pattern with cytologic atypia, invasive
Serous carcinoma
28
Which pathology of the uterus? Polyps in stroma and glands, associated with PID
Acute endometritis
29
Which pathology of the uterus? White whorled, well-circumscribed lesion, single or multiple
Leiomyoma
30
Which pathology of the vagina? Dense zone of small spindle cells with abundant mitoses and eosinophilic cytoplasm beneath the epithelium, striations may be visible in cytoplasm
Embryonal Rhabdomyosarcoma
31
Which pathology of the vagina? Mucinous epithelium associated with DES-exposure, may predispose to clear cell carcinoma
Adenosis
32
Which pathology of the vagina? Round, grape-like clusters that protrude from the vagina in a child
Embryonal Rhabdomyosarcoma
33
Which pathology of the vagina? Tubulocystic growth pattern with kissing lesion and barrel-like cervix
Clear Cell Carcinoma
34
Which pathology of the vulva? 1-5mm flesh-colored pearly lesions, spread by contact
Molluscum Contagiosum
35
Which pathology of the vulva? Adenocarcinoma with single tumor cells or cells that form clusters
Extramammary Paget Disease
36
Which pathology of the vulva? Dermal fibrosis with mononuclear infiltrate, thinned epidermis, hyperkeratosis
Lichen sclerosis
37
Which pathology of the vulva? Endophytic growth with eosinophilic inclusion bodies w/o ulceration or inflammation
Molluscum Contagiosum
38
Which pathology of the vulva? Hyperkeratosis, pale basal epidermis, specialized form of adenocarcinoma
Extramammary Paget Disease
39
Which pathology of the vulva? Hyperkeratosis, parakeratosis, koilocytes
Condyloma Acuminatum
40
Which pathology of the vulva? Increased mitoses, full thickness dysmaturity, hyperkeratosis, no invasion of basement membrane
VIN III/ CIS
41
Which pathology of the vulva? Infiltrating irregular nests of squamous cells with desmoplastic response, may demonstrate basaloid pattern
Squamous cell carcinoma
42
Which pathology of the vulva? Malignant neoplasm in women >70
Inflammatory-associated squamous cell carcinoma
43
Which pathology of the vulva? Malignant neoplasm in women under 60
HPV-associated squamous cell carcinoma
44
Which pathology of the vulva? Malignant neoplasm with poor prognosis, must be differentiated from Paget Disease
Melanoma
45
Which pathology of the vulva? Nuclear atypia, koilocytes, lack of maturation as cells progress to epithelial surface
VIN I/II
46
Which pathology of the vulva? Red, sharply demarcated crusted area on the vulva
Extramammary Paget Disease
47
Which pathology of the vulva? Skin lesions classically seen among children sharing towels
Molluscum Contagiosum
48
Which pathology of the vulva? Smooth white plaques with parchment with skin that cracks and bleeds easily
Lichen sclerosis
49
Which pathology of the vulva? White, exophytic growth, associated with HPV6/11
Condyloma Acuminatum
50
Which pathology? Intense pruritis with curdlike discharge
Candida
51
Which pathology? Non-pathogenic infection in context of copper IUD, sulfur granules with club-like projections
Actinomyces
52
Which pathology? Normal flora that can overgrow in the context of antibiotics, diabetes mellitus, or pregnancy
Candida