I: Female Pathology Flashcards

1
Q

Which pathology of the vulva? Painful red lesions 3-7 days after exposure; papules that become vesicles that may ulcerate

A

HSV

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2
Q

Which pathology of the vulva? Eosinophilic intranuclear inclusions, viral cytopathic effect

A

HSV

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3
Q

Cervical cancer staging is based on _______.

A

clinical factors

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4
Q

Uterin cancer staging is based on ______.

A

spread

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5
Q

Which pathology of the cervix? Dyspareunia and dysuria resulting from infection by a flagellated protozoan

A

Trichomonas

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6
Q

Which pathology of the cervix? Exophytic lesion with dilated glands and dense eosinophilic stroma

A

Cervical polyp

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7
Q

Which pathology of the cervix? Full thickness dysmaturity with infiltrating nests of cells

A

Squamous cell carcinoma

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8
Q

Which pathology of the cervix? Hyperchromasia, mucin depletion, luminal mitoses and high N:C ratio

A

Adenocarcinoma in situ

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9
Q

Which pathology of the cervix? Strawberry cervix with frothy yellow discharge

A

Trichomonas

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10
Q

Which pathology of the uterus? Adenocarcinoma associated with unopposed estrogen, obesity, and genetics

A

Endometriod adenocarcinoma

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11
Q

Which pathology of the uterus? Adenocarcinoma type that may arise from hyperplasia

A

Endometriod adenocarcinoma

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12
Q

Which pathology of the uterus? Adenocarcinoma with P53 mutations commonly

A

Serous carcinoma

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13
Q

Which pathology of the uterus? Adenocarcionoma type with PTEN and KRAS mutations commonly

A

Endometriod adenocarcinoma

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14
Q

Which pathology of the uterus? Bland smooth muscle cells with cigar-shaped nuclei

A

Leiomyoma

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15
Q

Which pathology of the uterus? Crowded glands with sparse stroma and nuclear atypia, invasive

A

Endometriod adenocarcinoma

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16
Q

Which pathology of the uterus? Endometrial glands and stroma in an extrauterine location

A

Endometriosis

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17
Q

Which pathology of the uterus? Endometrial glands and stroma in the myometrium

A

Adenomyosis

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18
Q

Which pathology of the uterus? Exophytic growth, disorganized glands out of phase with the menstrual cycle

A

Endometrial polyp

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19
Q

Which pathology of the uterus? Glandular crowding and architectural complexity, may have nuclear atypia

A

Complex Hyperplasia

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20
Q

Which pathology of the uterus? Infiltrating mass +/- hemorrhage/necrosis, most commonly metastasize to lungs

A

Leiomyosarcoma

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21
Q

Which pathology of the uterus? Larger and more aggressive type of adenocarcinoma

A

Serous carcinoma

22
Q

Which pathology of the uterus? Malignancy with epithelial and connective tissue components, heterologous tumors worsen prognosis

A

Carcinosarcoma

23
Q

Which pathology of the uterus? More common type of adenocarcinoma

A

Endometriod adenocarcinoma

24
Q

Which pathology of the uterus? Most common uterine tumor

A

Leiomyoma

25
Q

Which pathology of the uterus? Occurs in post-menopausal women, adenocarcinoma

A

Serous carcinoma

26
Q

Which pathology of the uterus? Occurs in pre-menopausal and perimenopausal women, adenocarcinoma

A

Endometriod adenocarcinoma

27
Q

Which pathology of the uterus? Papillary growth pattern with cytologic atypia, invasive

A

Serous carcinoma

28
Q

Which pathology of the uterus? Polyps in stroma and glands, associated with PID

A

Acute endometritis

29
Q

Which pathology of the uterus? White whorled, well-circumscribed lesion, single or multiple

A

Leiomyoma

30
Q

Which pathology of the vagina? Dense zone of small spindle cells with abundant mitoses and eosinophilic cytoplasm beneath the epithelium, striations may be visible in cytoplasm

A

Embryonal Rhabdomyosarcoma

31
Q

Which pathology of the vagina? Mucinous epithelium associated with DES-exposure, may predispose to clear cell carcinoma

A

Adenosis

32
Q

Which pathology of the vagina? Round, grape-like clusters that protrude from the vagina in a child

A

Embryonal Rhabdomyosarcoma

33
Q

Which pathology of the vagina? Tubulocystic growth pattern with kissing lesion and barrel-like cervix

A

Clear Cell Carcinoma

34
Q

Which pathology of the vulva? 1-5mm flesh-colored pearly lesions, spread by contact

A

Molluscum Contagiosum

35
Q

Which pathology of the vulva? Adenocarcinoma with single tumor cells or cells that form clusters

A

Extramammary Paget Disease

36
Q

Which pathology of the vulva? Dermal fibrosis with mononuclear infiltrate, thinned epidermis, hyperkeratosis

A

Lichen sclerosis

37
Q

Which pathology of the vulva? Endophytic growth with eosinophilic inclusion bodies w/o ulceration or inflammation

A

Molluscum Contagiosum

38
Q

Which pathology of the vulva? Hyperkeratosis, pale basal epidermis, specialized form of adenocarcinoma

A

Extramammary Paget Disease

39
Q

Which pathology of the vulva? Hyperkeratosis, parakeratosis, koilocytes

A

Condyloma Acuminatum

40
Q

Which pathology of the vulva? Increased mitoses, full thickness dysmaturity, hyperkeratosis, no invasion of basement membrane

A

VIN III/ CIS

41
Q

Which pathology of the vulva? Infiltrating irregular nests of squamous cells with desmoplastic response, may demonstrate basaloid pattern

A

Squamous cell carcinoma

42
Q

Which pathology of the vulva? Malignant neoplasm in women >70

A

Inflammatory-associated squamous cell carcinoma

43
Q

Which pathology of the vulva? Malignant neoplasm in women under 60

A

HPV-associated squamous cell carcinoma

44
Q

Which pathology of the vulva? Malignant neoplasm with poor prognosis, must be differentiated from Paget Disease

A

Melanoma

45
Q

Which pathology of the vulva? Nuclear atypia, koilocytes, lack of maturation as cells progress to epithelial surface

A

VIN I/II

46
Q

Which pathology of the vulva? Red, sharply demarcated crusted area on the vulva

A

Extramammary Paget Disease

47
Q

Which pathology of the vulva? Skin lesions classically seen among children sharing towels

A

Molluscum Contagiosum

48
Q

Which pathology of the vulva? Smooth white plaques with parchment with skin that cracks and bleeds easily

A

Lichen sclerosis

49
Q

Which pathology of the vulva? White, exophytic growth, associated with HPV6/11

A

Condyloma Acuminatum

50
Q

Which pathology? Intense pruritis with curdlike discharge

A

Candida

51
Q

Which pathology? Non-pathogenic infection in context of copper IUD, sulfur granules with club-like projections

A

Actinomyces

52
Q

Which pathology? Normal flora that can overgrow in the context of antibiotics, diabetes mellitus, or pregnancy

A

Candida