I: Female Pathology Flashcards
Which pathology of the vulva? Painful red lesions 3-7 days after exposure; papules that become vesicles that may ulcerate
HSV
Which pathology of the vulva? Eosinophilic intranuclear inclusions, viral cytopathic effect
HSV
Cervical cancer staging is based on _______.
clinical factors
Uterin cancer staging is based on ______.
spread
Which pathology of the cervix? Dyspareunia and dysuria resulting from infection by a flagellated protozoan
Trichomonas
Which pathology of the cervix? Exophytic lesion with dilated glands and dense eosinophilic stroma
Cervical polyp
Which pathology of the cervix? Full thickness dysmaturity with infiltrating nests of cells
Squamous cell carcinoma
Which pathology of the cervix? Hyperchromasia, mucin depletion, luminal mitoses and high N:C ratio
Adenocarcinoma in situ
Which pathology of the cervix? Strawberry cervix with frothy yellow discharge
Trichomonas
Which pathology of the uterus? Adenocarcinoma associated with unopposed estrogen, obesity, and genetics
Endometriod adenocarcinoma
Which pathology of the uterus? Adenocarcinoma type that may arise from hyperplasia
Endometriod adenocarcinoma
Which pathology of the uterus? Adenocarcinoma with P53 mutations commonly
Serous carcinoma
Which pathology of the uterus? Adenocarcionoma type with PTEN and KRAS mutations commonly
Endometriod adenocarcinoma
Which pathology of the uterus? Bland smooth muscle cells with cigar-shaped nuclei
Leiomyoma
Which pathology of the uterus? Crowded glands with sparse stroma and nuclear atypia, invasive
Endometriod adenocarcinoma
Which pathology of the uterus? Endometrial glands and stroma in an extrauterine location
Endometriosis
Which pathology of the uterus? Endometrial glands and stroma in the myometrium
Adenomyosis
Which pathology of the uterus? Exophytic growth, disorganized glands out of phase with the menstrual cycle
Endometrial polyp
Which pathology of the uterus? Glandular crowding and architectural complexity, may have nuclear atypia
Complex Hyperplasia
Which pathology of the uterus? Infiltrating mass +/- hemorrhage/necrosis, most commonly metastasize to lungs
Leiomyosarcoma
Which pathology of the uterus? Larger and more aggressive type of adenocarcinoma
Serous carcinoma
Which pathology of the uterus? Malignancy with epithelial and connective tissue components, heterologous tumors worsen prognosis
Carcinosarcoma
Which pathology of the uterus? More common type of adenocarcinoma
Endometriod adenocarcinoma
Which pathology of the uterus? Most common uterine tumor
Leiomyoma
Which pathology of the uterus? Occurs in post-menopausal women, adenocarcinoma
Serous carcinoma
Which pathology of the uterus? Occurs in pre-menopausal and perimenopausal women, adenocarcinoma
Endometriod adenocarcinoma
Which pathology of the uterus? Papillary growth pattern with cytologic atypia, invasive
Serous carcinoma
Which pathology of the uterus? Polyps in stroma and glands, associated with PID
Acute endometritis
Which pathology of the uterus? White whorled, well-circumscribed lesion, single or multiple
Leiomyoma
Which pathology of the vagina? Dense zone of small spindle cells with abundant mitoses and eosinophilic cytoplasm beneath the epithelium, striations may be visible in cytoplasm
Embryonal Rhabdomyosarcoma
Which pathology of the vagina? Mucinous epithelium associated with DES-exposure, may predispose to clear cell carcinoma
Adenosis
Which pathology of the vagina? Round, grape-like clusters that protrude from the vagina in a child
Embryonal Rhabdomyosarcoma
Which pathology of the vagina? Tubulocystic growth pattern with kissing lesion and barrel-like cervix
Clear Cell Carcinoma
Which pathology of the vulva? 1-5mm flesh-colored pearly lesions, spread by contact
Molluscum Contagiosum
Which pathology of the vulva? Adenocarcinoma with single tumor cells or cells that form clusters
Extramammary Paget Disease
Which pathology of the vulva? Dermal fibrosis with mononuclear infiltrate, thinned epidermis, hyperkeratosis
Lichen sclerosis
Which pathology of the vulva? Endophytic growth with eosinophilic inclusion bodies w/o ulceration or inflammation
Molluscum Contagiosum
Which pathology of the vulva? Hyperkeratosis, pale basal epidermis, specialized form of adenocarcinoma
Extramammary Paget Disease
Which pathology of the vulva? Hyperkeratosis, parakeratosis, koilocytes
Condyloma Acuminatum
Which pathology of the vulva? Increased mitoses, full thickness dysmaturity, hyperkeratosis, no invasion of basement membrane
VIN III/ CIS
Which pathology of the vulva? Infiltrating irregular nests of squamous cells with desmoplastic response, may demonstrate basaloid pattern
Squamous cell carcinoma
Which pathology of the vulva? Malignant neoplasm in women >70
Inflammatory-associated squamous cell carcinoma
Which pathology of the vulva? Malignant neoplasm in women under 60
HPV-associated squamous cell carcinoma
Which pathology of the vulva? Malignant neoplasm with poor prognosis, must be differentiated from Paget Disease
Melanoma
Which pathology of the vulva? Nuclear atypia, koilocytes, lack of maturation as cells progress to epithelial surface
VIN I/II
Which pathology of the vulva? Red, sharply demarcated crusted area on the vulva
Extramammary Paget Disease
Which pathology of the vulva? Skin lesions classically seen among children sharing towels
Molluscum Contagiosum
Which pathology of the vulva? Smooth white plaques with parchment with skin that cracks and bleeds easily
Lichen sclerosis
Which pathology of the vulva? White, exophytic growth, associated with HPV6/11
Condyloma Acuminatum
Which pathology? Intense pruritis with curdlike discharge
Candida
Which pathology? Non-pathogenic infection in context of copper IUD, sulfur granules with club-like projections
Actinomyces
Which pathology? Normal flora that can overgrow in the context of antibiotics, diabetes mellitus, or pregnancy
Candida
