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Life Cycle > I: Male Pathology > Flashcards

I: Male Pathology Flashcards

1
Q

______ prostate zone: inverted cone with base at the base of the prostate and apex at the verumonatorum

A

Central

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2
Q

______ prostate zone: Surrounding zone posteriorly, laterally, and apically

A

Peripheral

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3
Q

______ prostate zone: two lobes surrounding prostatic urethra laterally and anteriorly

A

Transition

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4
Q

_______: squamous cell CIS involving genital skin

A

Bowen’s Disease

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5
Q

_______: squamous cell CIS involving mucosal surface of uncircumcized glans penis

A

Erythroplasia of Queyrat

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6
Q

______: site of prostatic urethra merging with ejaculatory ducts, at which the urethra makes a 35-degree bend

A

Verumonatorum

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7
Q

Best marker for detection, staging, and monitoring of patients with prostate cancer

A

PSA

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8
Q

BPH most commonly occurs in the _____ zone.

A

Transition

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9
Q

Most common cause of infectious epididymitis/orchitis in children

A

Gram negative rods

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10
Q

Most common cause of infectious epididymitis/orchitis in sexually active adults

A

Neisseria, Chlamydia

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11
Q

Most common cause of infectious epididymitis/orchitis in the elderly

A

Enterobacteria

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12
Q

Prostate cancer is assigned a _____ grade based on similarity of glandular architecture to normal

A

Gleason

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13
Q

Prostatic adenocarcinoma most commonly occurs in the ____ zone.

A

Peripheral

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14
Q

Varicocele more oftenly affects the ___ testis.

A

left

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15
Q

Which pathology? Aberrant phagocytic process with bacterial fragments calcifying within phagocytes

A

Malakoplakia

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16
Q

Which pathology? Arrest in germ cell development, thickening of basement membrane, Leydig cell hyperplasia, hyaline replacement

A

Cryptorchidism

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17
Q

Which pathology? Caseating granulomas part of systemic disease

A

Tuberculous Orchitis

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18
Q

Which pathology? Difficulty starting/stopping urination, increased urinary frequency, nocturia

A

BPH/adenocarcinoma

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19
Q

Which pathology? Diffuse mononuclear interstitial infiltrate rich in plasma cells, obliterative endarteritis, +/- gummas

A

Syphilis

20
Q

Which pathology? Dilation and tortuosity of veins in pampiniform plexus

A

Varicocele

21
Q

Which pathology? GCT in older men, cells resemble primary and secondary spermatocytes

A

Spermatocytic seminoma

22
Q

Which pathology? GCT that may cause gynecomastia and precocious puberty, granular eosinophilic cytoplasm with intracytoplasmic crystals

A

Leydig Cell Tumor

23
Q

Which pathology? GCT that secretes alpha-fetoprotein

A

Yolk Sac Tumor

24
Q

Which pathology? GCT with fish-flesh appearance

A

Seminoma

25
Q

Which pathology? GCT with frequent metastases, secretes beta-hCG

A

Choriocarcinoma

26
Q

Which pathology? GCT with heterogenous elements; good prognosis in children/variable in adults

A

Teratoma

27
Q

Which pathology? Inspissation of secretions to form sand-like substance in prostate

A

corpora amylacea

28
Q

Which pathology? Lymphocytic and plasma cell infiltration of prostate parenchyma

A

Chronic prostatitis

29
Q

Which pathology? Mononuclear inflammatory infiltrate with interstitial edema, infertility uncommon, usually subsequent to parotid involvement

A

Mumps orchitis

30
Q

Which pathology? More aggressive than seminomas, small tumors; large hyperchromatic pleomorphic nuclei and indistinct cytoplasm with frequent mitoses

A

Embryonal carcinoma

31
Q

Which pathology? Most common cancer in males

A

Prostatic Adenocarcinoma

32
Q

Which pathology? Most common penile cancer

A

Squamous Cell Carcinoma

33
Q

Which pathology? Most common testicular tumor in infants/children, loose/maze-like network of cells

A

Yolk Sac Tumor

34
Q

Which pathology? Most common testicular tumor in men over age 60

A

Lymphoma

35
Q

Which pathology? Most common type of germ cell tumor

A

Seminoma

36
Q

Which pathology? Neoplastic condition arising from condylomatous lesion with local invasion

A

Verrucous carcinoma

37
Q

Which pathology? Neutrophilic inflammation of prostate due to S. aureus, E. coli, or enterobacteria most commonly

A

Acute prostatitis

38
Q

Which pathology? Nodular aggregation of histiocytes containing calcified intracytoplasmic inclusions (_____ bodies)

A

Malakoplakia; Michaelis-Gutmann

39
Q

Which pathology? Occur in young men (15-35) with painless testicular enlargement

A

Germ Cell Tumor

40
Q

Which pathology? Placental differentiation with cytotrophoblasts and syncytiotrophoblasts

A

Choriocarcinoma

41
Q

Which pathology? Tubular sclerosis, Leydig cell hyperplasia, infertility

A

Klinefelter Syndrome

42
Q

Which pathology? Tuffed, papillary, or cribriform proliferation of atypical cells surrounded by basal cell layer (Prostate)

A

Prostatic Intraepithelial Neoplasia

43
Q

Which pathology? Undescended testes located anywhere along the path of descent

A

Cryptorchidism

44
Q

Which pathology? Uniform population of large polygonal cells with distinct cell membrane, clear cytoplasm, central nucleus; may have hCG-producing giant cells

A

Seminoma

45
Q

Which pathology? Variable glandular and stromal hyperplasia with dilatation of glands and papillary infoldings (Prostate)

A

BPH

46
Q

Which pathology? Yellowish or inapparent nodule, proliferation of cuboidal or columnar cells in a single-layered epithelium (prostate)

A

Adenocarcinoma

47
Q

Which typically occurs first: epididymitis or orchitis?

A

Epididymitis

Life Cycle (24 decks)

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