Hypersensitivity Responses Flashcards
1
Q
Type I
A
• IgE dependent (antibody in serum) • Cytokine IL-4 Produced • B-cell response • B-cells produce more IgE Mediators and cytokines are released
2
Q
Type II
A
• Self-reactive T-cells are released
• Produce IgE and IgM
Mediate cell death
3
Q
Type III
A
• Antibody mediated
• Form immune complexes in the blood
• Neutrophils are recruited
Degranulation
4
Q
Type IV
A
• T-cell mediated
• Cytokines produced by activated macrophages
Inflammatory responses
requires gamma interferon production
5
Q
Type V
A
• Antibody mediated dysfunction
Similar process to type II except function is lost
