Antimicrobial Chemotherapy

Question 1

What is a bactericidal?

Answer 1

an antimicrobial that kills bacteria i.e the penicillins

Question 2

What is a bacteriostatic?

Answer 2

an antimicrobial that inhibits growth of bacteria e.g. erythromycin

Question 3

Define sensitive.

Answer 3

an organism is considered sensitive if it is inhibited or killed by levels of the antimicrobial that are available at the site of infection.

Question 4

Define resistant.

Answer 4

an organism is considered resistant if it is not killed or inhibited by levels of the antimicrobial that are available at the site of infection.

Question 5

Define MIC.

Answer 5

Minimal inhibitory concentration is defined as the minimum concentration of antimicrobial needed to inhibit visible growth of a given organism.

Question 6

Define MBC

Answer 6

Minimal bactericidal concentration is defined as the minimum concentration of the antimicrobial needed to kill a given organism.

Question 7

Define topical

Answer 7

applied to surface, usually skin or to mucous membranes e.g. conjunctiva

Question 8

Define systemic

Answer 8

taken internally, either orally of parenterally

Question 9

Define parenteral

Answer 9

administered either intra-venously or intra-muscularly, occasionally subcutaneously