Antimicrobial Chemo

Question 1

What are examples of Beta-Lactam antibiotics?

Answer 1

Penicillins and cephalosporins

Question 2

How do beta-lactams effect bacteria?

Answer 2

inhibit cell wall synthesis

Question 3

Examples of Glycopeptides?

Answer 3

vancomycin

teicoplanin

Question 4

What type of bacteria are Glycopeptides active on? and how?

Answer 4

Gram positive

inhibit cell wall synthesis

Question 5

What are examples of aminoglycosides?

Answer 5

gentamicin

Question 6

What do aminoglycosides effect?

Answer 6

inhibit protein synthesis

Question 7

what do Glycopeptides effect?

Answer 7

cell wall synthesis

Question 8

what are macrolides?

Answer 8

antibiotics that work on protein synthesis

Question 9

examples of macrolides?

Answer 9

erythromycin

clarithromycin

Question 10

what do fluoroquinolones inhibit?

Answer 10

DNA synthesis

Question 11

Examples of fluoroquinolones?

Answer 11

ciprofloxacin

Question 12

When can gentamicin be used?

Answer 12

gram negative infections

Question 13

what could be used instead of penicillin in gram positive infections?

Answer 13

erythromycin

clarithromycin

Question 14

what can ciprofloxacin be used for?

Answer 14

gram negative organisms

Question 15

what infection can the use of cephalosporins (broad agent beta lactam) induce?

Answer 15

C.Diff infection

Question 16

when can daptomycin be used?

Answer 16

gram positives

particularly MRSA

Question 17

when can linezolid be used?

Answer 17

orally against MRSA

Question 18

how is vancomycin given?

Answer 18

toxic
given IV
allows careful control
should be infused slowly over a few hours

Question 19

can children use ciprofloxacin?

Answer 19

no

Question 20

how can you treat a beta-lactamase producing staph. A infection?

Answer 20

flucloxacillin

Question 21

what can be used against a C.Diff infection?

Answer 21

vancomycin
metronidazole
fidaxomicin

Question 22

how should gentamicin be given?

Answer 22

carefully controlled IV

monitor serum levels

Question 23

what is used in HIV therapy?

Answer 23

saquinavir

Question 24

what is used only in the treatment of a UTI?

Answer 24

nitrofurantoin

Question 25

a serious gram negative infection would require?

Answer 25

gentamicin

Question 26

a systemic fungal infection would require?

Answer 26

amphotericin B

Question 27

what should be used to treat an unknown gram negative bacteria?

Answer 27

gentamicin

Question 28

what is used topically or in oral suspension for serious fungal infections?

Answer 28

nystatin