Hormones and Hormone-like Products That Act in Digestion Flashcards
Gastrin
Source • Stomach Stimulus for secretion • Food in stomach, particularly partially digested proteins; ACh released by nerve fibers Action • Stimulates release of gastric juice • Stimulates stomach emptying
Intestinal gastrin
Source • Duodenum Stimulus for secretion • Food in stomach Action • Stimulates gastric secretion and emptying
Histamine
Source • Stomach Stimulus for secretion • Food in stomach Action • Activates parietal cells to secrete hydrochloric acid
Somatostatin
Source
• Stomach and duodenum
Stimulus for secretion
• Food in stomach stimulated by sympathetic nerve fibers
Action
• Inhibits secretion of gastric juice and pancreatic juice
• Inhibits emptying of stomach and gallbladder
Secretin
Source
• Duodenum
Stimulus for secretion
• Acidic chyme and partially digested foods in duodenum
Action
• Increases output of pancreatic juice rich in bicarbonate ions
• Increases bile output by liver
• Inhibits gastric mobility and gastric gland secretion
Cholecystokinin (CCK)
Source
• Duodenum
Stimulus for secretion
• Fatty chyme and partially digested proteins in duodenum
Action
• Increases output of enzyme-rich pancreatic juice
• Stimulates gallbladder to expel stored bile
• Relaxes sphincter of duodenal papilla to allow bile and pancreatic juice to enter the duodenum
Gastric inhibitory peptide (GIP)
Source • Duodenum Stimulus for secretion • Food in duodenum Action • Inhibits secretion of gastric juice • Stimulates insulin release