Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PH 166 > Hormones > Flashcards

Hormones Flashcards

1
Q

Which is false
A. Proteins have longer half-life than steroids
B. Steroids are bound to carrier protein
C. Steroids have cholesterol as precursor
D. Proteins have big size, that’s why they can’t enter the cell

A

A - shorter :)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
not an amino acid derivative
A. epinephrine
B. norepinephrine
C. thyroxine
D. estrogen
A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
among amino acid derivatives, which is a bound carrier?
A. epinephrine
B. norepinephrine
C. thyroxine
D. estrogen
A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

enumerate 3 main actions of hormones

A

growth and development
regulation of energy production, use and storage
homeostatic control of metabolic pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which endocrine gland secretes melatonin? Indicate also what melatonin does
A.pineal gland
B.anterior pituitary gland
C.posterior pituitary gland

A

A. Melatonin maintains body’s circadian rhythm & timing + release of female reproductive hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which endocrine gland has hormone prod c/o CNS?
A.pineal gland
B.anterior pituitary gland
C.posterior pituitary gland

A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which endocrine gland produces mostly peptides/glycoproteins for hormones?
A.pineal gland
B.anterior pituitary gland
C.posterior pituitary gland

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Differentiate positive feedback from negative feedback

A

Positive feedback: rate of process increases, product conc increases
Negative feedback: rate of process decreases, product conc increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

False about prolactin
A. acts at the hypothalamus to inhibit GnRH secretion
B. major circulating form: nonglycosylated monomer
C. measured by immunometric assay
D. not affected by diurnal variations

A

D - highest levels attained during sleep & a nadir occurring bet 10AM and noon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A. Levels of prolactin greater than 200 ng/mL signify: ___

B. enumerate 2 causes of prolactin deficiency

A

A. prolactinoma

B. pituitary necrosis / pseudohypoparathyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A.pre-dominating species of somatotropin

B.most useful form of somatotropin for GHD deficiency diagosis @

A

A.IGF-BP3
B.IGF-I
C.Stage 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
How is somatotropin measured? (generally)
A.chemiluminescent immunoassay
B.insulin tolerance test
C.somatomedin C
D.glucose suppression test
A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
GH deficiency test gold standard
A.chemiluminescent immunoassay
B.insulin tolerance test
C.somatomedin C
D.glucose suppression test
A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q 
screening test for acromegaly
A.chemiluminescent immunoassay
B.insulin tolerance test
C.somatomedin C
D.glucose suppression test
A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q 
confirmatory test for acromegaly
A.chemiluminescent immunoassay
B.insulin tolerance test
C.somatomedin C
D.glucose suppression test
A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which is false?
A.Thyroid-stimulating hormones push for iodide uptake
B.Fasting serum is used in growth hormone tests
C.Specimen for adrenocorticotropic hormone are stored in polyethylene tubes

A

C - polystyrene dapat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

A.Which part of the posterior pituitary gland produces anti-diuretic hormone?
B.Which part of the posterior pituitary gland produces oxytocin?

A

A.supraoptic nuclei

B.paraventricular nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A.Oxytocin stimulates contraction of the gravid uterus at term. What is this reflex called?
B.T/F Oxytocin scretion is inhibited by stressful situations

A

A.Fergusson reflex

B. T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q 
Does not inhibit release of ADH?
A.ethanol
B.cortisol
C.lithium
D.emetic
A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

A.diagnostic test for ADH abnormality

B.T/F posterior pituitary homrones are synthesized in the hypothalamus

A

A.overnight water deprivation test

B.T

21
Q

Which is false?
A.T4 is a major fraction of organic iodine in circulation
B.Elevated thyroxine causes inhibition of TSH secretion
C.Increase in T3 plasma level is the first sign of hypothyroidism

A

C - hyper dapat

22
Q

Which thyroid hormone binding protein is also known as transthyretin?
A.thyroxine-binding globulin
B.thyroxine-binding prealbumin
C.thyroxine-binding albumin

A

B

23
Q

Which thyroid hormone binding protein transports majority of thyroid hormones?
A.thyroxine-binding globulin
B.thyroxine-binding prealbumin
C.thyroxine-binding albumin

A

A

24
Q

Which thyroid hormone binding protein takes care of mostly T3?
A.thyroxine-binding globulin
B.thyroxine-binding prealbumin
C.thyroxine-binding albumin

A

C

25
Q

A.Differentiate primary hyperthyroidism from secondary hyperthyroidism
B. what is subclinical hyperthyroidism?

A

A.primary - elevated thyroid hormones, dec TSH
secondary - increased TSH & T4

B.TSH low, T3 & T4 normal

26
Q

Differentiate primary, secondary & tertiary hyporthyroidism

A

primary - deficiency of elemental iodine
secondary - pituitary adenoma
tertiary - hypothalamic disease

27
Q

A. what is thyrotoxicosis?
B. identify most common cause of thyrotoxicosis
C. how is B diagnosed?

A

A. caused by high levels of free TH in circulation
B. Grave’s disease
C. TSH Receptor antibody test

28
Q

A.identify disease where thyroid is replaced by lymphoid tissue
B.screening test result for congenital hypothyroidism
C.confirmatory test result for congenital hypothyroidism

A

A. Hashimoto’s disease
B. dec T4
C. inc TSH

29
Q

A.What does your thyrotropin releasing hormone stimulation test measure?
B.T/F More TRH means hyperthyroidism.
C.T/F TRH test = most impt thyroid func test

A

A.relationship bet TRH & TSH secretion
B.F - hypo dapat
C.F - TSH dapat

30
Q

A.Radioactive Iodine Uptake measures ___

B.Reference method for free T4 meas

A

A.ability of thyroid to trap iodine

B.equilibrium dialysis

31
Q

Which is false?
A.Decreased TSH does not happen in primary hypothyroidism
B.Decreased amount of thyroid hormones happens in Graves’ disease
C.Decreased TSH happens in Hashimoto’s disease

A

C -increase dapat

32
Q

Which is false about parathyroid hormone (PTH)?
A.As Ca levels increase, PTH secretion accelerates
B.PTH prevents hypocalcemia
C.PTH is produced by smallest endocrine gland in the body

A

A - dapat suppressed

33
Q

False about primary hyperparathyroidism
A.due to presence of PT adenoma
B.accompanied by phosphaturia
C.needs Ca supplementation to maintain Ca needs

A

C - this is for hypoparathyroidism. hypercalcemia ang problem @ primary hyperparathyroidism

34
Q

Which is false?
A.Renin-angiotensin system controls mineralocorticoids
B.Zona reticularis is the site of mineralocorticoid synthesis
C.Cortisol was synthesized in zona fasciculata
D.Secretions of adrenal gland affect BP

A

B - zona reticularis is for androstenedione & dehydroepiandrosterone. mineralocorticoids @ zona glomerulosa

35
Q 
False about cortisol
A.mostly bound to transcortin
B.stimulates gluconeogenesis @ liver
C.blood sample not affected by diurnal variation
D.metabolites are present @ urine
A

C - Urine ang di apektado, kaya urine ang the best. Blood sample must be collected @ 8AM

36
Q

A. Identify disease: due to autoimmune adrenalitis TB, hemorrhage, HIV. this disease leads to primary adrenal insufficiency
B. screening test for primary adrenal insufficiency

A

A. Addison’s disease

B. ACTH stimulation test

37
Q

A.most common form of congenital adrenal hyperplasia

B.definitive diagnosis for primary adrenal insufficiency

A

A.21-hydroxylase deficiency

B.impaired response to ACTH

38
Q

False about aldosterone
A.main determinant of renal excretion of potassium
B.most potent glucocorticoid
C.controlled by RAS

A

B - mineralocorticoid dapat

39
Q

A.What does aldosterone need for synthesis?
B.Primary hyperaldosteronism is also called __
C. diagnostic test for hypoaldosteronism

A

A.18-hydroxysterol dehydrogenase
B.Conn’s disease
C.furosemide stimulation test

40
Q

A.screening test for primary hyperaldosteronism
B.confirmatory test for secondary hyperaldosteronism
C.positive result for both

A

A.plasma aldosterone/renin activity
B.saline suppression test
C.> 5 ng/dL aldosterone

41
Q

A.precursor of catecholamines
B.highest conc of norepinephrine is in __
C.major metabolite of norepinephrine in CSF & urine

A

A.L-tyrosine
B.CNS
C.3-methoxy-4-hydroxyphenylglycol

42
Q 
false about epinephrine
A.most abundant medullary hormone
B.decreases glucose concentration
C.major metabolite is vanillymandelic acid
D.produced from norepinephrine
A

B - increase dapat

43
Q 
false  about pheochromocytoma
A. tumors of adrenal medulla
B. commonly seen in children
C. due to overprod of catecholamines
D. classic spells include  tachycardia and sweating
A

B - 30s and 50s dapat

44
Q

false about neuroblastoma
A. decreased production of norepinephrine
B. commonly seen in children
C. positive - high urinary excretion of vanillymandelic acid

A

A

increased dapat

45
Q

A. screening test for pheochromocytoma
B. diagnostic test for pheochromocytoma
C. @ radioimmunoassay, identify amount range that is indicative of pheochromocytoma

A

A. high plasma metanephrines & normetanephrines c/o HPLC
B. high 24h urinary excretion of metanephrines & normetanephrines
C. > 2000 pg/mL

46
Q

false about receptor-based assays
A. greater sensitivity than both bioassays and immunoassays
B. reflect biological function of the hormone, pero in-vitro
C. simple to perform

A

A - less sensitive than immunoassays

47
Q

enumerate 4 ways on how to measure hormone levels

A

bioassay
receptor-based assay
immunoassay
instrumental

48
Q

3 instrumental techniques used to measure hormone levels: enumerate

A

matrix-assisted laser ionization
electrolyte ionization
gas chromatograhy-mass spectrometry

PH 166 (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions