Hormones

Question 1

1. Steroid hormones, by binding specific nuclear receptors,
   have a direct effect on:
   a. enzyme phosphorylation.
   b. gene expression.
   c. cAMP formation.
   d. DNA replication.

Answer 1

b. gene expression.

Question 2

2. When a protein hormone binds a cell membrane receptor,
   the classical result is:

a. phosphorylation of intracellular enzymes.
b. inhibition of mRNA within the cell nucleus.
c. replication of DNA and division of the cell.
d. glycosylation of intracellular proteins

Answer 2

a. phosphorylation of intracellular enzymes.

Question 3

3. An example of an amino acid–related hormone would be:
   a. testosterone.
   b. thyroid hormone.
   c. growth hormone.
   d. prostaglandin

Answer 3

b. thyroid hormone.

Question 4

4. Which of the following hormones is classified as a polypeptide?

a. Cortisol
b. Estrogen
c. Adrenocorticotropic hormone
d. Thyroid hormone

Answer 4

c. Adrenocorticotropic hormone

Question 5

5. The type of hormone assay that best reflects hormone
   functionality as opposed to quantification of the hormone
   itself is the:

a. receptor-based assay.
b. mass spectrometry–based assays.
c. bioassay technique.
d. liquid chromatography

Answer 5

a. receptor-based assay.

Question 6

6. A hormone released from the pancreas in response to a
   glucose load that is involved in cellular energy production
   is considered to be involved in:
   a. modification of the response to stress.
   b. synthesis of milk proteins.
   c. promotion of bone development and growth
   d. homeostatic control of metabolism.

Answer 6

d. homeostatic control of metabolism.

Question 7

Which of the following is a characteristic of steroid hormones?

A. account for the majority of hormones
B. circulate freely
C. water soluble
D. long half life in the circulation

Answer 7

D. long half life in the circulation