Gastric, Pancreatic, and intestinal Function

Question 1

1. Gastrin
   a. is secreted by the liver and stomach.
   b. is secreted when stomach pH is low.
   c. stimulates gastric acid secretion.
   d. inhibits secretion of intrinsic factor

Answer 1

c. stimulates gastric acid secretion.

Question 2

2. The hydrogen breath test using glucose or lactulose as a
   substrate assesses

a. intestinal bacterial overgrowth.
b. celiac disease.
c. the presence of H. pylori.

Answer 2

a. intestinal bacterial overgrowth.

Question 3

3. A peptide neurotransmitter that relaxes smooth muscle in
   the gut and increases water and electrolyte secretion is
   a. cholecystokinin (CCK).
   b. secretin.
   c. vasoactive intestinal polypeptide (VIP).
   d. gastric inhibitory polypeptide.

Answer 3

a. cholecystokinin (CCK).

Question 4

4. The three phases of the digestive process include the neurogenic, gastric, and the intestinal phases. The intestinal
   phase is initiated
   a. by distention of the stomach.
   b. by the sight, smell, and taste of food.
   c. upon stimulation of the cerebral cortex in the brain.
   d. when weakly acidic digestive products of proteins and
   lipids enter the duodenum.

Answer 4

d. when weakly acidic digestive products of proteins and
lipids enter the duodenum.

Question 5

5. An example of an invasive test for detection of H. pylori in
   peptic ulcer disease would be

a. breath testing following ingestion of 14C­labeled urea.
b. microbiologic culture of a gastric biopsy sample.
c. lab measurement of a specific IgG antibody.
d. detection of a specific fecal antigen.

Answer 5

b. microbiologic culture of a gastric biopsy sample.

Question 6

6. Which one of the following is considered to be a disease of
   the intestine?
   a. Zollinger­Ellison syndrome
   b. Peptic ulcer disease
   c. Celiac disease
   d. Cystic fibrosis (CF)

Answer 6

c. Celiac disease

Question 7

7. In Western countries, the most common cause of chronic
   pancreatitis in adults is
   a. gallstones.
   b. infections.
   c. pancreatic tumors.
   d. alcohol consumption.

Answer 7

d. alcohol consumption.

Question 8

8. Which one of the following peptides stimulates increased
   pancreatic secretion of bicarbonate?

a. Glucose­dependent insulinotropic peptide (GIP)
b. Gluten
c. Secretin
d. Vasoactive intestinal polypeptide (VIP)

Answer 8

c. Secretin

Question 9

9. A tumor of the pancreatic islet cells that produces in part
   massive gastric hypersecretion, diarrhea, and steatorrhea
   causes
   a. the Zollinger­Ellison syndrome.
   b. celiac disease.
   c. lactose intolerance.
   d. cystic fibrosis (CF).

Answer 9

a. the Zollinger­Ellison syndrome.