Hormonal Regulation of Glucose Metabolism Flashcards

1
Q

steps in cellular uptake of glucose

A

glucose -> blood -> cellular uptake -> metabolism -> glucose-6-phosphate

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2
Q

METABOLISM of glucose to form energy

A

glycolysis

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3
Q

FORMATION of glycogen to store excess glucose

A

glycogenesis

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4
Q

where does the majority of glucose stored?

A

liver

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5
Q

secondary storage of glucose

A

muscle (small amount)

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6
Q

stored glucose are used during ____

A

starvation

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7
Q

BREAKDOWN of stored glycogen

A

glycogenolysis

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8
Q

FORMATION of glucose from non-carbohydrate source (AA,FA)

A

gluconeogenesis

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9
Q

conversion of carbohydrates to FATTY ACIDS

A

lipogenesis

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10
Q

BREAKDOWN of fatty acids

A

lipolysis

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11
Q

happens if glucose is absent

A

ketones = fats will become the source of energy

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12
Q

a process that happens when your body doesn’t have enough carbohydrates to burn for energy, and what will be the end result?

A

ketosis -> comatose

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13
Q

INSULIN

  • Effects on PG: increase or decrease
  • source:
  • promotes:
A
  • Effects on PG: increase
  • promotes:
    cellular uptake
    glycolysis
    glycogenesis
    lipogenesis
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14
Q

Glucagon

  • source:
  • promotes:
A
  • source: pancreas (alpha cells)
  • promotes:
    glycogenolysis
    gluconeogenesis
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15
Q

Somatostatin

  • source:
  • promotes:
A
  • source: pancreas (delta cells)
  • promotes:
    paracrine regulation of insulin and glucagon
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16
Q

Cortisol

  • source:
  • promotes:
A
  • source: adrenal cortex
  • promotes: gluconeogenesis
    lipolysis
17
Q

Epinephrine

  • source:
  • promotes:
A
  • source: adrenal medulla
  • promotes:
    glycogenolysis
    lipolysis
18
Q

Adrenocorticotropic hormone (ACTH)

  • source:
  • promotes:
A
  • source: anterior pituitary gland
  • promotes:
    glycogenolysis
    gluconeogenesis
    cortisol secretion
19
Q

Growth Hormone (GH)

  • source:
  • promotes:
A
  • source: anterior pituitary gland
  • promotes:
    (-) cellular uptake
    (-) glycolysis - insulin antagonist
20
Q

Thyroxine

  • source:
  • promotes:
A
  • source: thyroid
  • promotes:
    intestinal absorption of glucose
    glycogenolysis
    gluconeogenesis
21
Q

Human Placental Lactogen (hPL)

  • source:
  • promotes:
A
  • source: placenta
  • promotes:
    insulin antagonist
    gestational DM