Fredrickson's Classification of Hyperlipoproteinemia Flashcards

1
Q

↑ Chylomicron/VLDL

A

↑ TAG (Triglyceride)

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2
Q

↑ LDL

A

↑ TC (Total Cholesterol)

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3
Q

What is elevated in Eruptive Xanthoma?

A

↑ TAG (Triglyceride)

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4
Q

What is elevated in Xanthelasma?

A

↑ TC (Total Cholesterol)

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5
Q

yellow pruritic papulonodules

a. Eruptive Xanthoma
b. Xanthelasma

A

a. Eruptive Xanthoma

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6
Q

yellow periorbital papules

a. Eruptive Xanthoma
b. Xanthelasma

A

b. Xanthelasma

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7
Q

Familial CHYLOMICRONemia or LPL deficiency

A

Type 1

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8
Q

Type 1 lipoprotein particle/s:

A

Chylomicron

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9
Q

Type 1 Lab Findings

A

↑ TG

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10
Q

Type 1 features

A

eruptive xanthoma
pancreatitis

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11
Q

Familial hyperCHOLESTEROLinemia

A

Type 2a

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12
Q

Type 2a lipoprotein particle/s:

A

LDL

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13
Q

Type 2a Lab Findings

A

↑ LDL
↑ TC

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14
Q

Type 2a features

A

Xanthelasma
premature CHD

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15
Q

Familial COMBINED hyperliporoteinemia

A

Type 2b

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16
Q

Type 2b lipoprotein particle/s:

A

LDL
VLDL

17
Q

Type 2b Lab Findings

A

↑ LDL
↑ TAG
↑ TC

18
Q

Familial dysBETAlipoproteinemia

A

Type 3

19
Q

Type 3 lipoprotein particle/s:

A

IDL
B-VLDL

20
Q

Type 3 Lab Findings

A

↑ TAG
↑ TC

21
Q

Type 3 features

A

Eruptive xanthoma
premature CHD

22
Q

Primary hyperTRIGLYceridemia

A

Type 4

23
Q

Type 4 lipoprotein particle/s:

A

VLDL

24
Q

Type 4 Lab Findings

A

↑ TAG

25
Q

Type 4 features

A

Eruptive xanthoma
may be associated w/ premature CHD

26
Q

MIXED hyperlipidemia

A

Type 5

27
Q

Type 5 lipoprotein particle/s:

A

CM
VLDL

28
Q

Type 5 Lab Findings

A

↑ TAG

29
Q

Type 5 features

A

Eruptive xanthoma
may be associated w/ premature CHD
Pancreatitis