HIGH YIELDS Flashcards
70% of cases come from what organism?
than whats next?
streptococcus pneumoniae
<60 years 60%
>60 years 70%
neisseria meningitidis
what is this disease?
- Mortality high, 15-35% range
- Hydrocephalus, cerebral edema common
- In one series, 22% had arterial complications
Pneumococcal Meningitis
what is this disease?
outbreaks, vaccine for serogroups W,A,C,Y at 12 yo and 16 yo
Meningococcal Meningitis
what is this disease?
food borne
unique ability to cross the intestinal barrier
newborns, pregnant, elderly
translocates from meninges into brain
rhomboencephalitis
vancomycin tx
Listeria monocytogenes
classic triad for bacterial meningitis?
fever,nuchalrigidity and altered mental status
more specific than sensitive
Test is positive if resistance to extension at the knee to > 135
OR pain in lower back or posterior thigh
what is this test?
kernigs sign
Positive test=flexion of the knees and hips
what is this test?
brudzinski’s neck sign
T/F, obtain head CT if any of the baseline clinical features are present?
role of head CT
atypical CSF findings for?
CSF WBCs can range <100 to >10,000 cells/mm^3
10% can present with mainly lymphocytes
when CSF-WBCs 100-1000
bacterial meningitis
atypical CSF findings for?
present with neutrophilic predominance
especially enter-viral meningitis
viral meningitis
atypical CSF findings for?
CSF glucose <10 mg/dl typical of_____?
bacterial meningitis
mumps, TB, fungi, lymphocytic choriomeningitis virus (LCMV), leptomeningeal carcinoma
multiplex PCR (BioFire FilmArray for ______)
meningitis/encephalitis panel
name a poor med ABx for inflamed meninges?
adequate and good?
piperacillin-tazobactam
1st gen cephalosporin
ceftriaxone, cefepime
meropenem
metronidazole
chloramphenicol
linezolid
quinolones
