COPD Flashcards

1
Q

COPD chest radiograph findings?

A

flattened diaphragms and hyperlucency of lung fields

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2
Q

COPD consists of?

A

chronic bronchitis
small airway disease
emphysema

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3
Q

chronic inflammation
narrowing and reductio of small airway
airway collapse

what is this?

A

chronic bronchitis

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4
Q

enlarged airspaces
destruction of alveolar walls

what is this?

A

emphysema

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5
Q

most important risk factor for COPD?

A

cigarette smoking

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6
Q

what percent of patients die from COPD do not smoke?

A

20%

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7
Q

three clinical cardinal symptoms of COPD?

A

dyspnea
shortness of breath
sputum

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8
Q

how is chronic bronchitis defined?

A

chronic productive cough for a total of 3 months in each of 2 successive years when all causes of chronic cough have been excluded

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9
Q

hypoxic pulmonary vasoconstriction?

A

shunting

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10
Q

a measure of how easily CO molecules transfer from the alveolar gas to the HgB of the red cells in the pulmonary circulation

A

diffusing capacity of lung for carbon monoxide (DLCO)

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11
Q

main cause of hypoxemia in COPD is?

A

V/Q mismatch

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12
Q

how do we confirm the diagnosis of COPD?

A
smoking, occupational exposure
physical exam
lab findings
spirometry
absence of alternative explanation
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13
Q

most important nonpharmacologic tx of COPD?

A

smoking cessation

oxygen

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14
Q

what are the meds for COPD?

A

beta agonists
muscurinic antagonist
inhaled corticosteroids
systemic steroids

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15
Q

when is LABA-ICS considered?

A

asthmatic component to the COPD

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16
Q

SABA albuterol side effects?

A

tachycardia
tremor
hypokalemia

17
Q

SAMA ipratropium side effects?

A

dry mouth
acute urinary retention
acute narrow angle glaucoma

18
Q

when are ICSs most useful?

A

high eosinophils or overlap of COPD and asthma

19
Q

side effects of inhaled glucocorticoids?

A
oral candidiasis
pneumonia
osteoporosis
-ca supplements
-vit D
-bisphosphonates
20
Q

this is an immunomodulatory agent that’s a PDE4 inhibitor that bronchdilates?

A

Roflumilast