HIGH YIELD Flashcards
most common primary diagnosis in the US
one third of adults have hypertension
hypertension
risk factors of hypertension?
CAD HF Stroke vascular disease ESRD Smoking, dyslipidemia, DM
effects of hypertension on heart disease and stroke?
increased arterial stiffness and increased after load
ischemic heart disease
left ventricular hypertrophy and left atrial enlargement
systolic and diastolic HF
effect of acute hypertension on brain?
cerebral edema
intracerebral hemorrhage
effect of chronic hypertension on the brain?
hypertensive encephalopathy
- cerebral edema
- lacunar type infarcts
- dementia
the deleterious effects of too low a blood pressure on cerebral perfusion in a patient with chronic hypertension can lead to?
cerebral hypo perfusion
causes of primary hypertension?
high intake of salt
genetics
obesity
lack of physical activity
affects 90-95% of population
causes of secondary hypertension?
renal disease primary hyperaldosteronism pheochromocytoma endocrine obstructive sleep apnea medications
the most common cause of secondary hypertension?
renal disease
- renal parenchymal disease
- -chronic kidney disease
- -polycystic kidney disease
- renal vascular disease
- -renal artery stenosis
- -fibromuscular hyperplasia
primary hyperaldosteroneism is what kind of hypertension?
caused by?
*effects?
secondary
adrenal adenoma
-conns syndrome
idiopathic adrenal hyperplasia
-most common cause
other
-familial hyperaldosteronism, adrenal carcinoma
*Na retention and increased IV volume, loss of potassium, loss of H+ leads to metabolic acidosis
pheochromocytoma is caused by?
adrenal tumor
excessive amounts of epinephrine and norepinephrine
resistent hypertension
main cause of endocrine hypertension?
cushing syndrome
thyroid disease
-hyperthyroidism
-hypothyroidism
meds that cause secondary hypertension?
*meds whose withdrawal cause secondary htn?
NSAIDs
drugs of abuse
-alcohol, cocaine
adrenergic meds
corticosteroids
oral contraceptive use, activates RAAS
*beta blocker and clonidine
according to AHA/ACC, standards define HTN as?
as 130/80
lifestyle mods?
weight loss
smoking cessation
exercise
*DASH, dietary approach to stop hypertension