Hepatitis C Flashcards

1
Q

Causa principal de enfermedad hepática crónica

A

Hepatitis C

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2
Q

2 tipos de cronicidad de hepatitis C

A

Cirrosis descompensada y carcinoma hepatocelular (genotipo 1)

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3
Q

2 manifestaciones hepáticas en cirrosis descompensada

A

Insuficiencia hepática, hipertensión portal hemorrágica

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4
Q

2 manifestaciones extrahepáticas en cirrosis descompensada

A

Vasculitis, DM2

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5
Q

Cx px pre ictérico

A

Fiebre, mialgias, náuseas, vómito, diarrea, fatiga, hepatalgia

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6
Q

Cx px ictérico

A

Ictericia, elevación enzimas hepáticas (>8x), elevación bilirrubinas, fosfatasa alcalina y deshidrogenasa láctica (>3x), hepatomegalia/hepatalgia

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7
Q

Estudio paraclínico ante sospecha

A

Anti-VHC

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8
Q

Estudio paraclínico confirmatorio

A

PCR-RNA-VHC

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9
Q

V o F: No es necesario en caso de infecciones agudas

A

Verdadero

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10
Q

¿Quiénes son candidatos a tx?

A

TODOS (>12 años) menos lo que tengan una expectativa de vida <1 año a pesar de medicamentos o trasplante hepático

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11
Q

¿Cuál es el objetivo del tx de hepatitis C?

A

Evitar el cáncer o cirrosis hepática

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12
Q

Px de prioridad

A

Fibrosis importante, cirrosis, px alto riesgo, manifestaciones extrahepáticas, receptores de injerto hepático, hemodiálisis + deseo embarazo

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13
Q

Tx de elección hepatitis C

A

Sofosbuvir-Velapatasivir

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14
Q

Tx de 2º elección hepatitis C

A

Glecaprevir-Pibrentasivir

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15
Q

3 factores de riesgo hepatitis C

A

VIH, relaciones sin condón, sexo en grupo

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16
Q

¿A quién evaluar?

A

Drogadictos, hemodiálisis, px con VIH

17
Q
A