HEME 3.83 Flashcards
what causes sickle cell disease
change of amino acid number 6 (Glu—->Val)
what is the average life span of a sicke cell
7-10 days
what causes sickle cell crisis
more adherents sickle cells, inability to flow well through small vessels
where is the sicke cell most wide spread
throughout africa, middle east, and parts of india and the mediterranean
this group of disorder arises as a result of diminished or absent prodduction of one or more of the globin chains
Thalassemias
where is Thalassemias prominant in the world
Parts of Africa, Mediterranean, middle East, India, Asia.
How are Thalassemia classified
after the gene that is affected
The consequence of impaired production of globin chains leads to RBCs being ______ and _____
Microcytic, hypochromic
where does the cancer occur in leukemias
with white blood cell precursors
what is the most common acute leukemia in adults
AML (acute myeloid leukemia)