HEME 3.83 Flashcards

1
Q

what causes sickle cell disease

A

change of amino acid number 6 (Glu—->Val)

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2
Q

what is the average life span of a sicke cell

A

7-10 days

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3
Q

what causes sickle cell crisis

A

more adherents sickle cells, inability to flow well through small vessels

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4
Q

where is the sicke cell most wide spread

A

throughout africa, middle east, and parts of india and the mediterranean

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5
Q

this group of disorder arises as a result of diminished or absent prodduction of one or more of the globin chains

A

Thalassemias

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6
Q

where is Thalassemias prominant in the world

A

Parts of Africa, Mediterranean, middle East, India, Asia.

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7
Q

How are Thalassemia classified

A

after the gene that is affected

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8
Q

The consequence of impaired production of globin chains leads to RBCs being ______ and _____

A

Microcytic, hypochromic

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9
Q

where does the cancer occur in leukemias

A

with white blood cell precursors

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10
Q

what is the most common acute leukemia in adults

A

AML (acute myeloid leukemia)

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