3.71 Flashcards
The Rh blood group system is more complex than ABO and is the second most important blood grounp system in terms of ________ medicine because of its high ________
transfusion, Immunogenicity
How many Rh antigens are there, and how many are common
about 50 antigens, only 5 are common
what type of Blood is truly a universal doner
O-
what the three other blood grouping systems mentioned in lecture
-Kell (K, can be + or -)
-Duffy (Fy, can Fya and Fyb and + or -)
Lewis (a and b plus + or -)
what are the 5 different components of blood that can be donated
- red cells
- white cells
- platelets
- fresh frozen plasma
- heat-treated plasma
what is the most important aspect of transfusion medicine
the avoid transfusion reactions
what are the five issues that may arise from bad blood transfusions and what issues arise with each
- Hemolytic -antigen-antibody reaction (may be fatel, and concurent with kidney failure)
- Non-Hemolytic - damaged blood products that release high levels of cytokines, fever chills
- Alergic - leads to rashes and itching
- volume overload - pulmonary edema
- transfer of bacteria - leading to endotoxemia and septicemia, potentially fatal
what are the three main tests designed to ensure that any blood transfused into a recipient is compatible with the donar and will not cause a transfusion reaction
blood grouping - ABO and Rh
antibody screen
cross match
when can hemolytic disease of a newborn (HDN) occure
when the mother is Rh Negative and the Baby is Rh Postive, usually only occurs after the first preganancy
what can be given to prevent HDN
Rh immune globulin
