HEME 2 Misc Info Flashcards
what is the Hierarchy of the lymphatic system
Lymph Capillaries < Lymph venules and veins < Lymph ducts
where does the thoracic duct drain
Left subclavian vein
when is the Thymus at its largest
at puberty
Hemostasis is designed to ensure that there is no major leakage of blood following injury and consists of a complex system of ________ and _________
proteins and enzymes
any local bleeding is arrested by an interaction between _______ and blood vessels _________ ____, followed by a cascade of _________ _______
platelets
endothelial cells
coagulation factors
what is a normal leverl of platelts
between 250,000 - 400,000 per cubic millimeter of blood
Tunica intima only conains ______ ___ and small amount of _____
-endothelial cells, Collagen
vasoconstrictive phase of vascular spasm it triggered by: (2)
- the direct injury itesef
- sympathetic nervous system
list two reasons the body needs “natural” anticoagulants
- Inactivate coagulation factors that escape the injury site
- maintain hemostatic balance between coagulation and anti-coagulation
what activates protein C
thrombomodulin-thrombin complex
What does t-PA stand for
tissue plasminogen activator
clinically, what is APTT most often used to monitor
Heparin therapy
what can “extra” factor replacement be given
after a surgical procedure and after trauma
what are the similarities and differences between Hemophilia A and vWF
similarities:
prolonged APTT
reduced factor Vlll clotting activity
differences
prolonged PT (because of failure in platelet-vessel wall
interaction
what is idiopathic thrombocytopenic purpura
autoimmune response to platelets, which are removed prematurely by the Reticuloendothelial system
