HEME 1.2 Flashcards
what type of test is the complete blood count (CBC)
Panel of tests that examines different parts of the blood
how many different points of information will the CBC give
11
what is the white blood cell count
count the actual number of white blood cells per volume of blood (increases with infection)
what can decrease WBC count
- some medication
- bone marrow failure
- chemotherapy
- congenital marrow aplasia (no bone marrow development)
what is included in a WBC count
% of each WBC (5 major types)
also included BAND NEUTROPHILS (immature)
what is and increase of lymphocytes an indication of
acute or chronic leukemia
what does the RBC count lower with, increase with
anemia, increases with loss of water (i.e diarrhea)
what should the amount of hemoglobin morror
the RBC count results
hematocrite mirrors what results
RBC count
what is hemoglobin compatible with
oxygen carrying capacity
how much of the mass in a RBC does hemoglobin make up
1/3
what are the 4 globin subunits complexed with
Iron
what symptoms does a low hemoglobin count cause
tiredness and weakness
What is the Mean corpuscular volume
measurment of the average size of RBC
what causes macrocytic cells and what causes microcytic cells
macrocytic (large RBC) - Vit. B12 deficiency
Microcytic - Iron deficiency or thalassemias
what is the mean corpuscular hemoglobin
HCH the avarage amound of oxygen-carrying hemoglobin inside the RBC
what types of cells tend to have a higher MCH, lower?
Macrocytic cells have more, microcytic cells have less
what is a deacreased MCHC (concentration) called and what is the cause
hypochromia - caused by iron defeciency and thalasemia
what is a increased MCHC (concentration) called and what is the cause
hyperchromia - burn patients, hereditary spherocytosis and rare congenital disorder.
what causes an increase in Red cell distribution width
some anemias (pernicious anemia) the amount of veriation in RBC size (anisocytosis) and varitation in shape
what is the variation of shape in a RBC called
poikilocytosis
what is the normal reference range in human red blood cells
11-15%
what is the lowered number of platelets called
thrombocytopenia
what does thje CMP consist of and what must a patient do before taking this test
A panel of 14 individual blood tests
typically a patient fasts for 10-14 hours before the blood is drawn for the test.
