Heart failure drugs

Question 1

What is heart failure?

Answer 1

Heart failure is when the heart is unable to pump blood in sufficient amounts to meet the body’s metabolic needs

Question 2

What is inotropic, chronotropic and dormotroptic?

Answer 2

The heart’s ability to squeeze is the inotropic effect, chronotropic is the heart rate, and dormotropic is the speed of the electrical impulses.

Question 3

What are the consequences of HF?

Answer 3

Blood supply is reduced to important organs, impaired kidney filtration, pulmonary edema

Question 4

What are the five main causes of heart failure?

Answer 4

CAD, hypertension, myocardial infarction, diabetes, and obesity

Question 5

What are the different classes of heart failure?

Answer 5

Class 1 is no physical activity limitations, class 2 is ordinary physical activity results in fatigue, dyspnea, or other symptoms, class 3 is marked limitations with physical activity, and class 4 is symptoms at rest or with no physical activity.

Question 6

What lab value relates to heart failure?

Answer 6

Brain naturetic peptide (BNP)

Question 7

What is a diagnostic tool used to diagnose heart failure?

Answer 7

Echocardiogram

Question 8

What do inotropic drugs do?

Answer 8

They increase the force of myocardial contraction

Question 9

What do chronotropic drugs do?

Answer 9

They increase heart rate

Question 10

What do dromotropic drugs do?

Answer 10

They accelerate cardiac conduction

Question 11

What drugs are used for early heart failure?

Answer 11

Lisinopril, valsartan, metoprolol

Question 12

What drug is used for heart failure after early treatment has been done?

Answer 12

Digoxin

Question 13

What is dobutamine and what is it used for?

Answer 13

It is a positive intropic drug drug used for heart failure

Question 14

What are the indication of lisinopril?

Answer 14

Hypertension, heart failure, acute myocardial infarction

Question 15

What is the main ARB used for heart failure?

Answer 15

Valsartan

Question 16

What is the main beta blocker used for heart failure?

Answer 16

Metoprolol

Question 17

What do ace inhibitors do to help heart failure?

Answer 17

They cause diuresis which decreases the blood volume and blood return to the heart (preload) which causes decreases workload of the heart

Question 18

What is important for ARBs related to heart failure?

Answer 18

They are vasodialtors and decrease vascular resistance (afterload)

Question 19

What drugs prevent ventricular remodelling and hypertrophy?

Answer 19

ARBs and ACE inhibitors

Question 20

What is phosphodiesterase inhibitors?

Answer 20

It is a drug that inhibits phophodiesterase. It is an inotropic drug and a vasodialtor

Question 21

WHat is the main drug example of Phosphodiesterase inhibitors?

Answer 21

Milirone

Question 22

What is the main cardiac glycoside example?

Answer 22

Digoxin

Question 23

What do cardiac glycosides do?

Answer 23

They increase heart contractility and decrease rate of electrical conduction so it has an inotropic and dormotropic effect

Question 24

What are the effects of cardiac glycosides?

Answer 24

Positive inotropic effect, negative chronotropic effect, and negative dromotropic effect

Question 25

What tropic effect does dobutamine illicit?

Answer 25

It is a postivie inotrope