Antiviral Drugs Flashcards
What is acyclovir?
This is a drug used to suppress HSV 1, 2 and VZV.
What are the main adverse effects of antiviral drugs?
They will often kill healthy cells leading to toxicities
What is amantadine used for related to viral infections?
It is a narrow antiviral drug used to treat influenza A
What is ganciclovir hydrochloride used for?
This is an antiviral used to treat cytomegalovirus (CMV). This is associated with decreased dose-limiting bone marrow suppression, causing blood cell productivity.
What is oseltamivir phosphate and zanamivir
These drugs are used to treat influenza types A and B.
What is Hepatitis c
This is a viral infection that causes chronic liver disease
What is the main drug to treat hepatitis c and what is its inhalation form?
Ribavirin. The inhalation form is called virazole with the respiratory viral infection
How do antiretroviral drugs work?
These drugs include three medications and work to reduce the viral load
What are reverse transcriptase inhibitors?
These are antiretroviral drugs that prevent the production of new viral DNA
What are the two types of reverse transcriptase inhibitors?
NRTIs and NNRTIs
What are protease inhibitors?
These are antiretroviral drugs that inhibit protease enzyme which prevents viral replication
What are fusion inhibitors?
These are antiretroviral drugs that inhibit viral fusion preventing viral replication
What is an example of an entry inhibitor?
Maraviroc
What is an example of an integrase inhibitor?
Raltegravir potassium
What is indinavir?
It is a protease inhibitor that reduces viral load and increases production of CD4 cells.
What is an adverse effect of indinavir and how is it fixed?
Kidney stones is an adverse effects and we fix this by drinking lots of fluids
What is zidovudine used in combination with?
It is used in combination with didanosine
What is an adverse effect of zidovudine?
It has a major dose-limiting effect of bone marrow suppression
What two retroviral drugs are often combined together?
Zidovudine and didanosine
What is enfuvirtide?
This is a fusion inhibitor drug
What is the drug combination used for chemoprophylaxis for occupational exposure to HIV
Tenofovir and lamivudine and raltegravir
WHat drug is used for the treatment of RSV in infants?
ribavirin
