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Pharmacology 2 > Cholinergic blocking drugs > Flashcards

Cholinergic blocking drugs Flashcards

1
Q

What are cholinergic blocking drugs?

A

They inhibit the actions of ACh in the parasympathetic system

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2
Q

What are examples of natural plant alkaloids that are cholinergic blocking drugs?

A

Atropine sulphate, and scopolamine hydrobromide

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3
Q

What are three synthetic and semisynthetic cholinergic blocking drugs?

A

Glycopyrrolate, oxybutynin. and tolterodine

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4
Q

What are the indications for cholinergic blocking drugs?

A

Decrease in muscle rigidity, bronchodilation, bronchospasms, COPD

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5
Q

What do high doses and low doses of cholinergic bloking drugs do?

A

They can result in an increase in heart rate for high dose and decrease in heart rate for small doses

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6
Q

What is atropine used for?

A

Cardiovascular disorders, sinus bradycardia,

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7
Q

What are the effects of anticholinergic drugs?

A

Dry mouth, confusion, constipation, urinary retention

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8
Q

What are the gastrointestinal effects of anticholinergic drugs?

A

Decreased GI secretions, relaxation of smooth muscle, decreased GI motility and peristalsis

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9
Q

What are the respiratory effects of anticholinergic drugs?

A

Decresed secretions, relaxed smooth muscle, bronchodilation

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10
Q

What are the genitourinary uses of anticholinergic drugs?

A

Reflex neurogenic bladder, and incontinence

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11
Q

What are the main contraindications for anticholinergic drugs?

A

GLAUCOMA, cardiovascular instability, anything that causes significant oxygen demand

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12
Q

What is the main disease we dont give people anticholinergic drugs to?

A

Glaucoma

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13
Q

What drug is given for anticholinergic overdose with extreme agitation and delirium?

A

Physostigmine

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14
Q

What do we want to monitor for patients on these drugs?

A

We want to monitor their heart so electrochardiogram

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15
Q

What are the drug interactions for this drug?

A

Amantadine, antihistamines, phenothiazines, and digoxin

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16
Q

What is atropine and what is it used for

A

It is a naturally occurring antimuscarinic. It is used for patients who code, bradycardia.

17
Q

What is glycopyrrolate?

A

It is a synthetic antimuscarinic drug that is used to control the production of secretions.

18
Q

What is oxybutynin?

A

It is a synthetic antimuscarinic drug used for overactive bladders

19
Q

What is scopolamine?

A

It is a natural cholinergic drug used to treat nausea from motion sickness.

20
Q

What is tolterodine?

A

It is a muscarinic receptor blocker that is used for urinary frequency and urgency

21
Q

What is a nursing consideration for this drug related to the eyes?

A

Patients become sensitve to light and should be given dark glasses afterwards

22
Q

What is the antidote for atropine overdose?

A

Physostigmine

Pharmacology 2 (20 decks)

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