Anti-inflammatory and antigout medication

Question 1

What are the three properties all NSAIDS share?

Answer 1

Antipyretic, analgesia, and anti inflmmatory

Question 2

What is an example of a salicylate NSAID

Answer 2

Aspirin

Question 3

What are acetic acid derivative NSAIDS?

Answer 3

Diclofenac, indomethacin, ketorolac

Question 4

What is an example of a cyclo-oxygenase inhibitor NSAID?

Answer 4

Celecoxib

Question 5

What are two examples of propionic acid deravitives?

Answer 5

Ibruprofen, naproxen

Question 6

What are the uses of aspirin?

Answer 6

Myocardial infarction, antiplatelet activity,

Question 7

What are the main contraindications for NSAIDS?

Answer 7

Vitamin k deficiency, rhinitis, peptic ulcer disease. (Patient is more likely to bleed)

Question 8

What are the significant adverse effects of NSAID use?

Answer 8

GI bleeding, ulcers, hepatotoxicity, altered hemostasis, kidney injury

Question 9

What is the main concern of NSAID

Answer 9

Gastric ulcers because they affect the protective layer.

Question 10

What is another concern of NSAIDs relating to the bodies filtering system?

Answer 10

They can affect kidney function and cause kidney damage

Question 11

What is an adverse effects of NSAIDs except aspirin?

Answer 11

They can cause cardiovascular thrombotic event.

Question 12

What are the 7 types of salicylates?

Answer 12

Acetylsalicylic acid, oral, topical liquid, oral liquid, supposiroty, aspirin-antacid combo, and enteric coated aspirin

Question 13

What does aspirin do?

Answer 13

It inhibits the aggregation of platelets and treatment of MI and thromboembolic events

Question 14

What are the doses for aspirin tablets?

Answer 14

81 and 325 mg

Question 15

What happens in salicylate toxicity?

Answer 15

Increased heart rate, hearing problems, altered blood glucose,

Question 16

What is indomethacin?

Answer 16

This is an NSAID with analgesic, anti-inflammatory, and antipyretic effects. It is used for the treatment of Rheumatoid arthritis, osteoarthritis, bursitis (INFLAMMATION)

Question 17

What is ketorolac and what is it used for?

Answer 17

It is an NSAID used for pain management becuase of its analgesia similar to narcotics

Question 18

What is ibuprofen?

Answer 18

It is the most commonly used NSAID that is used for pain specifcally RA and OA

Question 19

What is naproxen?

Answer 19

This is the second most used NSAID that has fewer drug adverse effects than ibuprofen

Question 20

What is celecoxib and what atients do we avoid giving this?

Answer 20

This is the only remaining COX2 inhibitor and is used for RA, OA, and pain. We dont give this to patients with sulpha allergy.

Question 21

What is used to treat NSAID adverse effects? what are the adverse effects?

Answer 21

Misoprostol is used to treat the GI bleeding and mucosal lesions

Question 22

What is GOUT?

Answer 22

It is a painful condition caused by inappropriate uric acid metabolism which causes them to be stored in the tissues and joints

Question 23

What does allopurinol do?

Answer 23

It prevents uric acid production

Question 24

What does probenecid do?

Answer 24

It inhibits the reabsorption of uric acid in the kidneys which causes excretion of uric acid

Question 25

What does colchine do?

Answer 25

This is an antigout medication used to reduce inflammatory response the body has to the uric acid deposits

Question 26

What is glucosamine and chondroitin?

Answer 26

They are herbal products used to treat pain from osteoarthritis

Question 27

What are significant contraindications for NSAIDs?

Answer 27

Gi lesions and Peptic ulcer disease

Question 28

What population should be avoided with salicylates and why is this? IMPORTANT

Answer 28

Children and teenagers are contraindicated because this drug causes reyes syndrome