Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology 2 > Antitubercular drugs > Flashcards

Antitubercular drugs Flashcards

1
Q

What are the main sites of infection

A

The lungs are main then sometimes the brain and bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What drugs are multidrug-resistant tuberculosis resistant to?

A

They are resistant to isoniazid and rifampin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the first-line drugs for tuberculosis?

A

Isoniazid, ethambutol, pyrazinamide, and rifampin acronym: RIPE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the three second line drugs?

A

Amikacin, Levofloxacin, moxifloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the primary antitubercular drug?

A

Isoniazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of the primary tuberculosis drugs cant be given to pregant women?

A

Pyrazinamide (pregnant)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of patients do you watch out for before giving isoniazid?

A

Slow acetylators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the main adverse effects of isoniazid? IMPORTANT

A

Peripheral neuritis, hepatotoxicity, hyperglycemia, discolouration of body fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is given to a patient on isoniazid to help the peripheral nueropathy?

A

Vitamin B6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a contraindication for ethambutol? IMPORTANT

A

Children under 13 years of age

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the adverse effects of ethambutol? IMPORTANT

A

Visual changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is a contraindication pyrazinamide? IMPORTANT

A

patients with gout and liver disease as well as pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the main adverse effects of rifampin? IMPORTANT

A

Discolouration of body fluids, hepatitis, and affects warfarin think red colouration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is PPD (purified protein derivative?

A

IT is a diagnostic injection used to detect the TB organism.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does a positive PPD look like?

A

There will be induration at the site of injection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the BCG (bacille calmette guerin)?

A

A vaccine injection taken from inactivated strain of the bacteria. Prevents severe cases of tuerculosis

17
Q

WHat is the main drug effect of therapy for tuberculosis?

A

Reduction of cough and infectiousness of the patient

18
Q

What is the best time to do a sputum culture for the client

A

In the morning to get the most accurate reading since there will be a high amount of bacteria in mouth

19
Q

What does it mean to be a slow acetylator

A

This means they dont have eenough enzymes in liver to metabolize a medication meaning the drug has longer effects in the body or even toxicity

20
Q

What test do we do for a person to be put onto rifampin and isoniazid?

A

A liver function study

21
Q

What test is used to diagnose tuberculosis

A

Stomach secretions, sputum culture, TB blood test

22
Q

What isolation precaution is for tuberculosis

A

Airborne precautions

23
Q

Why is more than one drug used when treating someone?

A

It reduces the chance of drug resistance happening

Pharmacology 2 (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions