Antifungal drugs Flashcards

1
Q

What is the primary site of infection for aspergillosis?

A

The lungs

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2
Q

What are the four types of fungal infections?

A

Cutaneous, subcutaneous, superficial, and systemic

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3
Q

What is terbinafine used to treat?

A

Athletes foot, toenails, fingernails

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4
Q

What drug is used to treat vaginal candida infections?

A

Nystatin and fluconazole

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5
Q

What medication is used to treat aspergillosis?

A

Voriconazole and capsofungin

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6
Q

What are the two main drugs used to treat systemic fungal infections?

A

Terbinafine and voriconazole

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7
Q

When should voriconazole be given

A

It should be given an hour before or after a meal

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8
Q

What is the main drug we use to treat severe systemic fungal infections?

A

Amphotericin B

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9
Q

What is the relationship with fluconazole and the blood brain barrier?

A

Fluconazole can pass into the cerebrospinal fluid, killing fungal infections there.

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10
Q

What is onychomycosis and what medication is used to treat it?

A

This is a nail infection and terbinafine is used to treat this

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11
Q

What is the main contraindication for fungal drugs

A

liver failure, kidney failure,

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12
Q

What is the only antifungal contraindicated in pregnant women?

A

Voriconazole

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13
Q

What are the adverse effects of amphotericin b?

A

Neurotoxicity, kidney toxicity,

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14
Q

WHat are premedications when using amphotericin b?

A

Antiemetics, antihistamines, antipyretics, and corticosteroids will all be given before amphotericin b to reduce the severity of infusion-related reactions.

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15
Q

What is candiada albicans?

A

This is a fungus that can grow in the mouth and is called thrush or oral candidiasis

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16
Q

What is amphotericin b lipid complex used over the clear solution

A

It is used beause it has fewer adverse effects

17
Q

What is a nursing implication for amphotericin b?

A

We monitor patients IV infusions every 15 to 30 minutes

18
Q

What is nystatin used to treat?

A

To treat fungal infections in the mouth. Oral candidasis

19
Q

How often are we checking vitals when someone is on amphotericin b

A

Every 15-30 minutes

20
Q

What is terbinafine used to treat?

A

Athletes foot, toenail and fingernail infection, and ring worm

21
Q

What do we call fungi that infect the integumentary system?

A

We call these dermatomycoses or dermatophytes