Antifungal drugs Flashcards
What is the primary site of infection for aspergillosis?
The lungs
What are the four types of fungal infections?
Cutaneous, subcutaneous, superficial, and systemic
What is terbinafine used to treat?
Athletes foot, toenails, fingernails
What drug is used to treat vaginal candida infections?
Nystatin and fluconazole
What medication is used to treat aspergillosis?
Voriconazole and capsofungin
What are the two main drugs used to treat systemic fungal infections?
Terbinafine and voriconazole
When should voriconazole be given
It should be given an hour before or after a meal
What is the main drug we use to treat severe systemic fungal infections?
Amphotericin B
What is the relationship with fluconazole and the blood brain barrier?
Fluconazole can pass into the cerebrospinal fluid, killing fungal infections there.
What is onychomycosis and what medication is used to treat it?
This is a nail infection and terbinafine is used to treat this
What is the main contraindication for fungal drugs
liver failure, kidney failure,
What is the only antifungal contraindicated in pregnant women?
Voriconazole
What are the adverse effects of amphotericin b?
Neurotoxicity, kidney toxicity,
WHat are premedications when using amphotericin b?
Antiemetics, antihistamines, antipyretics, and corticosteroids will all be given before amphotericin b to reduce the severity of infusion-related reactions.
What is candiada albicans?
This is a fungus that can grow in the mouth and is called thrush or oral candidiasis