Diuretic drugs Flashcards

1
Q

What is the main example of a carbonic anhydrase inhibitor?

A

Acetazolamide

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2
Q

What is the main use for carbonic anhydrase inhibitors?

A

GLAUCOMA

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3
Q

What is the main example of a loop diuretic?

A

Furosemide

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4
Q

What is the MOA of loop diuretics?

A

Drugs that act on the ascending loop of Henle to increase rate of diuresis

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5
Q

What is the onset of loop diuretics and how long does it last

A

It has a rapid onset and lasts 2 hours.

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6
Q

What are the indication for loop diuretics

A

EDEMA, hypertension, heart failure,

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7
Q

What is the main adverse effect of loop diuretics?

A

Hypokalemia

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8
Q

What is the most commonly used loop diuretic, and what is used for?

A

Furosemide is used for edema associated with heart failure and hypertension

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9
Q

What is the main example of an osmotic diuretic?

A

mannitol

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10
Q

What are the main effects of osmotic diuretics?

A

Increased glomerular filtration rate and renal plasma flow, prevents kidney damage, and prevents kidney damage from acute kidney injury

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11
Q

What is the main example of a potassium sparing diuretic?

A

Spironolactone, SP:sparing

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12
Q

What is the main example of thiazide and thiazide-like diuretics?

A

Hydrochlorothiazide

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13
Q

Thiazide should not be used when we see what lab values and what range for that value

A

We do not give thiazide if creatinine clearance is less than 30-50mL/min.

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14
Q

What is the main indication for thiazide-like diuretics?

A

Hypertension, edema

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15
Q

What electrolyte is important to diuretic drugs?

A

Patients shoud be taught to eat foods that are high in potassium.

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16
Q

What is a possible toxicity patient may experience while taking a diuretic?

A

Patients taking digoxin with a diuretic may experience digoxin toxicity

17
Q

What is something a specific patient group should measure and be aware of when taking diuretics?

A

diabetic patients should watch their blood glucose as that may be affected by the diuretic drugs.

18
Q

What is a contraindication for carbonic anhydrase inhibitors

A

hyponatremia, hypokalemia, kidney or liver dysfunction,

19
Q

What is the main interaction for carbonic anhydrase inhibitors?

A

We need to watch out for digoxin because carbonic anhydrase inhibitors can caused greater digoxin toxicity if they are taken together.

20
Q

What is the main sign of digoxin toxicity?

A

Very slow heart rate

21
Q

What is the main use of osmotic diuretics

A

Cerebral edema from intracranial pressure

22
Q

What is spironolactone able to do related to the heart

A

It is able to prevent heart remodelling

23
Q

What are the main thing we are monitoring when giving patients diuretic drugs?

A

We are mostly monitoring their fluid volume, ELECTROLYTES, especially potassium, and vital signs

24
Q

What is the most potent diuretic we give for rapid diuresis?

A

A loop diuretic