Headache Syndromes Flashcards
what are the red flag symptoms when a patient presents with headache (5)?
new onset headache >55 known/previous malignancy immunosuppression early morning headache exacerbated by valsalva
who is migraine more common in - males or females?
females
what is the average number of attacks in a month for patients with migraine?
one a month usually
what is the criteria for diagnosing migraine without aura?
> 5 attacks lasting 4-72 hours
two of = moderate/severe, unilateral, throbbing pain, worse on movement
one of = autonomic features, photophobia, nausea etc.
what is aura?
fully reversible visual, sensory, motor or language symptoms
how does migraine with aura present?
aura lasting 20-60 minutes, followed by migraine <1 hour later
state some examples of things that could trigger migraine
sleep diet stress hormones physical exertion
what drugs can be used as acute abortive agents in migraine?
NSAIDs
triptans
name some NSAIDs that can abort a migraine and the dose that should be given
aspirin 900mg
naproxen 250mg
ibuprofen 400mg
what are triptans?
5-HT agonists
what routes can triptans be administered by?
oral
sublingual
subcutaneous
name three triptans that can be used to abort a migraine
razatriptan
eletriptan
frovatriptan - for sustained relief
when should migraine prophylaxis be considered?
more than three attacks per month OR very severe attacks
what are the three options for migraine prophylaxis?
amitriptyline
propranolol
topiramate
what dose of amitriptyline should be given for migraine prophylaxis?
10-25mg
what are some possible adverse effects of amitriptyline?
dry mouth
postural hypotension
sedation
what dose of propranolol should be given for migraine prophylaxis?
80-240mg daily
what conditions are contraindications to propranolol?
asthma
PVD
what type of drug is topiramate?
carbonic anhydrase inhibitor
what dose of topiramate should be given as migraine prophylaxis?
25-100mg daily