Brain Tumours Flashcards

1
Q

what can worse the headache that brain tumours often preset with?

A

worse in the morning
coughing
leaning forward

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how many grades of astrocytic tumours are there?

A

four

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is a grade one astrocytic tumour called?

A

pilocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is a grade two astrocytic tumour called?

A

low grade astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is a grade three astrocytic tumour called?

A

anaplastic astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is a grade four astrocytic tumour called?

A

glioblastoma multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

who gets grade I astrocytic tumours?

A

children and young adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

is a grade I astrocytic tumour benign or malignant?

A

benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what four locations can be affected by grade I astrocytic tumours?

A

optic nerve
hypothalamus
cerebellum
brainstem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the treatment of choice for grade I astrocytic tumours?

A

surgery

it is curative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are the three types of grade II astrocytic tumours?

A

fibrillary
gemistocytic
protoplasmic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what areas of the brain tend to be affected by grade II astrocytic tumours?

A

temporal lobe
posterior frontal lobe
anterior parietal lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how can grade II astrocytic tumours present?

A

seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what happens to grade II astrocytic tumours over time?

A

dedifferentiate into high grade malignancies as they are not benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the treatment for grade II astrocytic tumours?

A

surgery and any of:

  • radio
  • chemo
  • combined radio and chemo
  • follow up serial imaging
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

are anaplastic astrocytomas benign or malignant?

A

malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is the median survival with anaplastic astrocytomas?

A

two years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is the most common primary brain tumour?

A

glioblastoma multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is the median survival with glioblastoma multiforme?

A

under a year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how do glioblastoma multiforme spread?

A

through white matter and CSF pathways

21
Q

what treatment can be done for glioblastoma multiforme?

A

non curative surgery to improve QoL

22
Q

what part of the brain is affected by oligodendroglial tumours?

A

frontal lobes

23
Q

what age group is most commonly affected by oligodendroglial tumours?

A

adults 25-45

24
Q

how do oligodendroglial tumours present?

25
are oligodendroglial tumours benign or malignant?
low grade benign but can undergo malignant conversion
26
how are oligodendroglial tumours managed?
surgery and chemotherapy
27
what is the median survival in oligodendroglial tumours?
ten years
28
how do the majority of meningiomas present?
asymptomatic
29
which sex is more commonly affected by meningiomas?
female
30
how can meningiomas present?
headaches | regional anatomical disturbances
31
how can meningiomas present if they affect the base of the skull?
cranial nerve neuropathies
32
are meningiomas malignant or benign?
the vast majority are benign
33
what are the four types of meningiomas?
classic angioblastic atypical malignant
34
how are meningiomas managed?
preoperative embolisation surgery radiotherapy
35
name three nerve sheath tumours
schwannomas neurofibromas malignant peripheral nerve sheath tumours
36
what is another name for a Schwannoma
neuroma
37
what is another name for an acoustic neuroma?
vestibular schwannoma
38
what condition are acoustic neuromas associated with?
neurofibromatosis II
39
how do acoustic neuromas present?
hearing loss tinnitus disequilibrium
40
what investigations are done for acoustic neuroma?
audiometry | radiology
41
how are acoustic neuromas managed?
radiation | surgery
42
what type of tumour are pineal tumours?
germ cell
43
who is usually affected by pineal tumours?
people under the age of 20
44
what imaging can be done for pineal tumours?
CT scan
45
how can pineal tumours metastasise?
via the CSF
46
what are the two main groups of pineal tumours?
germinomas | non germinomas
47
what is the most common CNS germ cell tumour?
germinomas
48
how can germinomas be managed?
radiation
49
name four non germinomatous pineal tumours
teratoma yolk sac tumour choriocarcinoma embryonal carcinoma