gout Flashcards
most common inflammatory arthritis…..
gout
gout
systemic disease caused by a disruption in purine metabolism in which uric acid crystals are deposited in joints and body tissues.
gout classified as
primary or secondary.
primary gout
- Most common form of gout
- Uric acid production is greater than excretion of it by the kidneys
- Can have a genetic component
Middle aged and older adult males
- Peak onset between ages 40 and 50
- Postmenopausal women are also commonly affected
secondary gout
Starts out as another disease or condition
- Usually chronic kidney failure
- Excessive diuretic use
- Causes excessive uric acid in the blood
- Treatment is based on treating the underlying condition
- Any age group is vulnerable
risk factors for gout
Obesity
Cardiovascular disease
Trauma
Alcohol ingestion
Starvation dieting
Diuretic use
Some chemotherapy agents
Chronic kidney failure
expected findings of gout
Severe joint pain
- Metatarsophalangeal joint of the great toe
- Redness
- Swelling
- Warmth of affected joint
- Painful joints that is more painful when touched or moved
- Appearance of tophi (chronic gout)
gout: Erythrocyte sedimentation rate (ESR):
eleavted
gout Serum uric acid:
Repeated measurements obtained due to effect of dietary intake on results.
- Consistent elevation above 6.5 mg/dL is associated with gout
gout: urinary uric acid
elevated
gout: Blood urea nitrogen (BUN), serum creatinine:
elevated
meds for acute gout
anti-gout
nsaids
corticosteroids
Anti-gout agent
Colchicine: decreases pain and inflammation
- Can cause kidney damage. Use cautiously with patients who have impaired kidney function
gout: NSAIDs
Indomethacin or ibuprofen: decreases pain and inflammation
- Can also cause kidney damage.
- Teach patients to take with food
gout: corticosteroids
Prednisone: decreases inflammation
- Monitor for fluid retention, hypertension, and renal function
- Teach patients to not stop taking medication abruptly. Doses must be tapered