adrenal gland Flashcards

1
Q

what does the adrenal cortext produce

A

produces glucocorticoids (cortisol), mineralocorticoids (aldosterone) and sex hormones.

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2
Q

drenal medulla produces

A

catecholamines epinephrine and norepinephrine

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3
Q

addisons disease

A

Adrenal insufficiency: The hyposecretion of adrenal cortex hormones

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4
Q

addisons caused by

A

Autoimmune disease
TB histoplasmosis
adrenalectomy
tumors
HIV
Can be induced by the abrupt cessation of steroid medications.

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5
Q

clinical manifestations of addisons

A
  • Weakness and fatigue
    • Nausea and vomiting
      -Hyperpigmentation
    • Hypotension
    • Increased heart rate
    • Hypoglycemia
    • Hyponatremia
    • Hyperkalemia
    • Hypercalcemia
  • sick all the time
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6
Q

what do you give addison

A

add cortisol

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7
Q

cushing disease caused

A
  • oversecretion of the hormones the adrenal cortex produces.
  • result of a tumor in the pituitary gland resulting in release of the hormone ACTH.
  • long‑term use of glucocorticoids to treat other conditions, such as asthma or rheumatoid arthritis.
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8
Q

age for cushings

A

20-40

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9
Q

causes of increased cortisol in cushings

A
  • Adrenal hyperplasia
  • Adrenocortical carcinoma
  • Pituitary carcinoma that secretes adrenocorticotropic hormone (ACTH)
  • Carcinomas of the lung, gastrointestinal (GI) tract, or pancreas (these tumors can secrete ACTH)
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10
Q

expected findings for cushings

A
  • Weakness, fatigue, sleep disturbances
  • Back and joint pain
  • Altered emotional state (irritability, depression)
  • Decreased libido
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11
Q

physical assessment findings for cushings

A
  • Evidence of decreased immune function and decreased inflammatory response (infections without fever, swelling, drainage, redness)
  • Thin, fragile skin
  • Bruising and petechiae (fragile blood vessels)
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12
Q

cushings physical assessment

A
  • Hypertension (sodium and water retention)
  • Tachycardia
    Gastric ulcers due to oversecretion of hydrochloric acid
  • Weight gain and increased appetite
  • Irregular menses
  • Dependent edema: Changes in fat distribution, including the characteristic fat distribution of moon face, truncal obesity, and fat collection on the back of the neck (buffalo hump)
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13
Q

cushings what they look like

A
  • Fractures (osteoporosis)
  • Bone pain and fractures with an increased risk for falls
  • Muscle wasting (particularly in the extremities)
  • Impaired glucose tolerance
  • Frequent infections, poor wound healing
  • Hirsutism
  • Acne
  • Red cheeks
  • Striae (reddened lines on the abdomen, upper arms, thighs)
  • Clitoral hypertrophy
  • Thinning, balding hair
  • Hyperglycemia
  • Emotional lability
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14
Q

test for cushing

A
  • dexamethasone supression test: Tests vary in length and amount of dexamethasone to administer.
  • 24-hr urine collections show suppression of cortisol excretion in clients who do not have Cushing’s disease.
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15
Q

diagnostic procedures

A
  • X-ray, magnetic resonance imaging, and CT scans identify lesions of the pituitary gland, adrenal gland, lung, GI tract, and pancreas.
  • Radiological imaging determines the source of adrenal insufficiency (tumor, adrenal atrophy).
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