GI pharm

Question 1

What drug categories are used to help with GI tract?

Answer 1

Acid suppression
	GI motility
	Laxatives
	IBD
Intestinal secretions

Question 2

What are the types of acid suppression?

Answer 2

Antacids
Alginates
H2-receptor antagonists
Proton pump inhibitors

Question 3

What are the drugs that affect GI motility?

Answer 3

Anti-emetics
Anti-muscarinics/other anti-spasmodics
Anti-motility
Other muscosal protectors (bismuth, sucralfate, misoprostol)

Question 4

What drugs can help intestinal secretions?

Answer 4

Cholestyramine

Ursodeoxycholic Acid

Question 5

Describe the types of acid suppresion drugs - antacids

Answer 5

Antacids (e.g. Maalox)
— Contain magnesium or aluminium
— Neutralise gastric acid
— Taken when symptoms occur

Question 6

Describe alginates

Answer 6

Alginates (e.g. Gaviscon)

— Form a viscous gel that floats on stomach contents and reduces reflux

Question 7

Describe H2 blockers

Answer 7

H2-receptor antagonists (e.g. Ranitidine)
— Block histamine receptor thereby reducing acid secretion
— Indicated in GORD/Peptic ulcer disease
— Given orally or intravenously
— Gl side effects

Question 8

What are the types of laxative?

Answer 8

Bulk (isphagula)
	Osmotic (lactulose)
	Stimulant (senna)
	Softeners (archis oil)
Work by increasing bulk or drawing fluid into gut