Genes in populations 3 Flashcards
roughly when did hominids and other great apes diverge?
5.7 million years ago
what are the 2 arguments for where humans arose?
multi regional vs out of Africa
what is the multi regional theory?
a single population spread over many continents connected by gene flow with high genetic diversity and transitioned from H. erectus to H. sapiens
what is the out of Africa theory?
humans originated out of a limited area of Africa with a low genetic diversity H. sapiens replaced H.erectus
2 pieces of evidence to support out of Africa model
1) compared to our closest relatives humans are not very diverse
2) all alleles share a common ancestor
5 features of mitochondrial DNA
1) found in both sexes
2) maternally inherited only
3) small molecules
4) high mutation rate
5) many copies per cell
3 features of Y chromosome DNA
1) found in males only
2) paternally inherited only
3) do not recombine with X chromosome
when did humans emerge in Africa and when did they spread?
the emerged 120-140 thousand years ago and they spread 30-80 thousand years ago
what is evidence go show that skin colour is adaptive?
dark skin in Africa to protect from UV - little Vitamin D produced so more needed in diet
light skin in Europe due to high grain diet with low vitamin D and low UV levels
what is the gene best studied for pigmentation?
MCR1
how is lactase persistent inherited?
autosomal dominant mendelian trait - persistance allele is dominant to lactose intolerance allele
what are heterozygotes to cystic fibrosis resistant to?
cholera and typhoid
why is there a higher frequency of cystic fibrosis heterozygotes in Europe?
because they are resistant to infectious diseases which are more common in agricultural societies
when did agriculture and domestication take place?
within the last 10 thousand years
what is cladogenesis?
the formation of a new group of organisms by evolutionary divergence (speciation)