Fundamentals: Chapter 31 Flashcards
What is the chemical name of a medication?
An exact description of its composition and molecular structure
What is the generic name of a medication?
the name given to a medication by the manufacturer who first develops it
What is the trade name of a medication?
the name under which a manufacturer markets a medication
What is a medication classification?
indicates the effect of the medication on a body system, the symptoms the medication relieves, or its desired effect
What is the study of how medications enter the body, reach their site of action, metabolize, and exit the body?
pharmacokinetics
What is the passage of medication molecules into the blood from the site of medication administration?
absorption
What route of administration produces the most rapid absorption?
IV
When is medication absorption complete?
When it is absorbed into the blood
Which three factors effect the ability of a medication to dissolve?
Blood flow to the site of administration
Body surface area
Lipid solubility
How does body surface area effect absorption of medications?
large surface area = faster absorption rate
Which three factors effect the distribution of a medication?
Circulation
Membrane permeability
Protein binding
What kind of medications can pass through the blood-brain barrier?
fat-soluble
How does protein binding effect distribution of a medication?
medications bound to albumin cannot exert pharmacological activity
How does age effect protein binding?
Older adults have less protein, therefore less medication binds to protein which leads to increased med activity and/or toxicity.
What happens to medication once it reaches the site of action?
it becomes metabolized into a less active or inactive form that is easier to excrete
What is the term for the removal of the toxic quality of a substance?
detoxify
Where does most biotransformation occur?
liver
Where is a medication excreted after metabolism?
Kidneys, Liver, bowel, lungs, and exocrine glands
What is the purpose of deep breathing and coughing?
helps patients to eliminate anesthetic gases more rapidly
What is the main organ for medication excretion?
kidney
What are the types of medication actions?
Therapeutic
Adverse
Side
Toxic
Idiosyncratic
Allergic
What is the therapeutic effect?
the expected or predicted physiological response to a medication
What is a side effect?
predictable and often unavoidable secondary effects produced at a usual therapeutic dose