Forces acting across membranes 1-3 Flashcards
Glycoprotein
Carbohydrate and protein
Glycolipid
Carbohydrate and lipid
Na+ is high in
ECF but also a little bit of K+
Why is there more K+ in ECF than Na+ in ICF?
Easier for potassium to get out of cells due to leaky membrane
Peripheral proteins
Maintain structure, anchor to matrix and signal functions
Less protein = good or bad insulator?
Good eg myelin sheath
High protein = high/low activity?
High eg mitochondria 75%
Electrical gradient
Difference in charge of ions across the membrane
Electrogenic pump
Creates charge difference across the membrane with a net movement of positive out of cell
What 3 features do the lipid bilayer favour?
Small, uncharged and lipophilic
Carrier mediated
If opposes movement require an ATPase
H20 conc proportional to?
1/ solute conc
Osmotic pressure
Pressure applied to oppose osmosis
Osmolarity
Total number of solute particles
mOSMOL/L
Normal human plasma osmolarity
300 (285) mOSMOL/L
Osmotic flux
If particle cannot cross the membrane water will move to compensate
Non penetrating particle in ICF
potassium
Non penetrating particles in ECF
Sodium and chlorine
Tonicity
Number of non penetrating particles in solution
Cells in hypotonic solutions
Swell
Cells in hypertonic solutions
Shrink