Blood Flashcards
How much blood in body?
5L - 3L in venous systemic circulation
350 ml in newborn baby
Functions of blood
Defence, carry gas, clotting, thermoregulation, carry active compounds, pH
Plasma made up of
Dissolved enzymes, nutrients, hormones and waste
Plasma proteins
Albumin, globulin, fibrinogen
Colloid oncotic pressure
Proteins cannot cross capillary wall so pull water in - change in volume
Fluid movement depends on
COP and hydrostatic pressure
Hypoproteinaemia
Less protein in blood due to liver or kidney disease or starvation
What do all blood cells come from?
Pluripotent bone marrow
Erythropoesis
RBC formation and accelerated by erythropoietin
2-3 day delay
Viscosity
How thick blood is compared to water
plasmax1.8blood x3-4
Leukopoesis
Controlled by cocktail of cytokines to form WBC
Platlets
Membrane bround fragments adhere to damaged blood vessel
Haematocrit
% of RBC in whole blood
Female less than male about 35%
Bilrubin
Broken down RBC